PDB entry 1qur
View 1qur on RCSB PDB site
Description: human alpha-thrombin in complex with bivalent, benzamidine-based synthetic inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: trypsin like serine protease, blood coagulation, hydrolase-hydrolase inhibitor complex
Deposited on
1999-07-02, released
1999-10-14
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.209
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: human thrombin (beta chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1qur.1 - Chain 'I':
Compound: bivalent inhibitor (bza-2 hirulog)
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: human thrombin (alpha chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1qur.1 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>1qurH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqf
- Chain 'I':
No sequence available.
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>1qurL (L:)
adcglrplfekksledkterellesyi