PDB entry 1qur

View 1qur on RCSB PDB site
Description: human alpha-thrombin in complex with bivalent, benzamidine-based synthetic inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: trypsin like serine protease, blood coagulation, hydrolase-hydrolase inhibitor complex
Deposited on 1999-07-02, released 1999-10-14
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.209
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: human thrombin (beta chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1qur.1
  • Chain 'I':
    Compound: bivalent inhibitor (bza-2 hirulog)
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1QUR (0-18)
  • Chain 'L':
    Compound: human thrombin (alpha chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1qur.1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1qurH (H:)
    ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
    vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
    pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
    itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
    thvfrlkkwiqkvidqf
    

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1qurL (L:)
    adcglrplfekksledkterellesyi