PDB entry 1qs8

View 1qs8 on RCSB PDB site
Description: crystal structure of the p. vivax aspartic proteinase plasmepsin complexed with the inhibitor pepstatin a
Class: hydrolase
Keywords: plasmepsin, aspartic proteinase, haemoglobinase, malaria, pepstatin a, hydrolase
Deposited on 1999-06-25, released 1999-07-07
The last revision prior to the SCOP 1.75 freeze date was dated 2003-05-27, with a file datestamp of 2007-07-06.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.197
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: plasmepsin
    Species: Plasmodium vivax
    Database cross-references and differences (RAF-indexed):
    • gb g3095034 (2-328)
    Domains in SCOP 1.75: d1qs8a_
  • Chain 'B':
    Compound: plasmepsin
    Species: Plasmodium vivax
    Database cross-references and differences (RAF-indexed):
    • gb g3095034 (2-328)
    Domains in SCOP 1.75: d1qs8b_
  • Chain 'C':
    Compound: pepstatin A
  • Chain 'D':
    Compound: pepstatin A
  • Heterogens: ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1qs8A (A:)
lgsendvielddvanimfygegevgdnhqkfmlifdtgsanlwvpskkcnssgcsiknly
dssksksyekdgtkvditygsgtvkgffskdlvtlghlsmpykfievidtddlepiyssv
efdgilglgwkdlsigsidpivvelknqnkidnalftfylpvhdvhagyltiggieekfy
egnityeklnhdlywqidldvhfgkqtmekanvivdsgtttitapseflnkffanlnvik
vpflpfyvttcdnkemptlefksanntytlepeyymnpilevddtlcmitmlpvdidsnt
filgdpfmrkyftvfdydkesvgfaiakn

    Sequence, based on observed residues (ATOM records): (download) 
    >1qs8A (A:)
sendvielddvanimfygegevgdnhqkfmlifdtgsanlwvpskkcnssgcsiknlyds
sksksyekdgtkvditygsgtvkgffskdlvtlghlsmpykfievidtddlepiyssvef
dgilglgwkdlsigsidpivvelknqnkidnalftfylpvhdvhagyltiggieekfyeg
nityeklnhdlywqidldvhfgkqtmekanvivdsgtttitapseflnkffanlnvikvp
flpfyvttcdnkemptlefksanntytlepeyymnpilevddtlcmitmlpvdidsntfi
lgdpfmrkyftvfdydkesvgfaiakn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1qs8B (B:)
lgsendvielddvanimfygegevgdnhqkfmlifdtgsanlwvpskkcnssgcsiknly
dssksksyekdgtkvditygsgtvkgffskdlvtlghlsmpykfievidtddlepiyssv
efdgilglgwkdlsigsidpivvelknqnkidnalftfylpvhdvhagyltiggieekfy
egnityeklnhdlywqidldvhfgkqtmekanvivdsgtttitapseflnkffanlnvik
vpflpfyvttcdnkemptlefksanntytlepeyymnpilevddtlcmitmlpvdidsnt
filgdpfmrkyftvfdydkesvgfaiakn

    Sequence, based on observed residues (ATOM records): (download) 
    >1qs8B (B:)
gsendvielddvanimfygegevgdnhqkfmlifdtgsanlwvpskkcnssgcsiknlyd
ssksksyekdgtkvditygsgtvkgffskdlvtlghlsmpykfievidtddlepiyssve
fdgilglgwkdlsigsidpivvelknqnkidnalftfylpvhdvhagyltiggieekfye
gnityeklnhdlywqidldvhfgkqtmekanvivdsgtttitapseflnkffanlnvikv
pflpfyvttcdnkemptlefksanntytlepeyymnpilevddtlcmitmlpvdidsntf
ilgdpfmrkyftvfdydkesvgfaiakn

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.