PDB entry 1qo3

View 1qo3 on RCSB PDB site
Description: Complex between NK cell receptor Ly49A and its MHC class I ligand H-2Dd
Class: receptor/immune system
Keywords: RECEPTOR/IMMUNE SYSTEM, COMPLEX (NK RECEPTOR-MHC CLASS I), NK CELL, INHIBITORY RECEPTOR, MHC-I, C-TYPE LECTIN-LIKE, HISTOCOMPATIBILITY, B2M, LY49, LY-49, RECEPTOR-IMMUNE SYSTEM complex
Deposited on 1999-11-01, released 2000-01-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-04-15, with a file datestamp of 2015-04-10.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MHC class I h-2dd heavy chain
    Species: Mus musculus [TaxId:10090]
    Gene: H-2D
    Database cross-references and differences (RAF-indexed):
    • PDB 1QO3
    • Uniprot P01900 (1-End)
    Domains in SCOPe 2.06: d1qo3a1, d1qo3a2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: MUS MUSCULUS [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1QO3 (0-0)
      • variant (85)
    • Uniprot P01887 (1-99)
    Domains in SCOPe 2.06: d1qo3b2, d1qo3b3
  • Chain 'C':
    Compound: ly49a
    Species: MUS MUSCULUS [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20937 (0-End)
      • engineered mutation (0)
      • variant (40)
      • variant (97)
    Domains in SCOPe 2.06: d1qo3c_
  • Chain 'D':
    Compound: ly49a
    Species: MUS MUSCULUS [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20937
      • variant (40)
      • variant (97)
    Domains in SCOPe 2.06: d1qo3d_
  • Chain 'P':
    Compound: hiv envelope glycoprotein 120 peptide
    Species: HUMAN IMMUNODEFICIENCY VIRUS, synthetic [TaxId:12721]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1qo3A (A:)
    mshslryfvtavsrpgfgeprymevgyvdntefvrfdsdaenpryeprarwieqegpeyw
    eretrrakgneqsfrvdlrtalryynqsaggshtlqwmagcdvesdgrllrgywqfaydg
    cdyialnedlktwtaadmaaqitrrkweqagaaerdraylegecvewlrrylkngnatll
    rtdppkahvthhrrpegdvtlrcwalgfypaditltwqlngeeltqemelvetrpagdgt
    fqkwasvvvplgkeqkytchveheglpepltlrwgke
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qo3A (A:)
    shslryfvtavsrpgfgeprymevgyvdntefvrfdsdaenpryeprarwieqegpeywe
    retrrakgneqsfrvdlrtalryynqsaggshtlqwmagcdvesdgrllrgywqfaydgc
    dyialnedlktwtaadmaaqitrrkweqagaaerdraylegecvewlrrylkngnatllr
    tdppkahvthhrrpegdvtlrcwalgfypaditltwqlngeeltqemelvetrpagdgtf
    qkwasvvvplgkeqkytchveheglpepltlrwg
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1qo3B (B:)
    miqktpqiqvysrhppengkpnilncyvtqfhpphieiqmlkngkkipkvemsdmsfskd
    wsfyilahteftptetdtyacrvkhasmaepktvywdrdm
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1qo3C (C:)
    stvldslqhtgrgdkvywfcygmkcyyfvmdrktwsgckqtcqssslsllkiddedelkf
    lqlvvpsdscwvglsydnkkkdwawidnrpsklalntrkynirdggcmllsktrldngnc
    dqvficicgkrldkfph
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qo3C (C:)
    stvldslqhkvywfcygmkcyyfvmdrktwsgckqtcqssslsllkiddedelkflqlvv
    psdscwvglsydnkkkdwawidnrpsklalntrkynirdggcmllsktrldngncdqvfi
    cicgkrld
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1qo3D (D:)
    stvldslqhtgrgdkvywfcygmkcyyfvmdrktwsgckqtcqssslsllkiddedelkf
    lqlvvpsdscwvglsydnkkkdwawidnrpsklalntrkynirdggcmllsktrldngnc
    dqvficicgkrldkfph
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qo3D (D:)
    dkvywfcygmkcyyfvmdrktwsgckqtcqssslsllkiddedelkflqlvvpsdscwvg
    lsydnkkkdwawidnrpsklalntrkynirdggcmllsktrldngncdqvficicgkrld
    k
    

  • Chain 'P':
    No sequence available.