PDB entry 1qk1

View 1qk1 on RCSB PDB site
Description: crystal structure of human ubiquitous mitochondrial creatine kinase
Class: transferase (creatine kinase)
Keywords: transferase (creatine kinase), mitochondrial creatine kinase, cancer, cellular energy metabolism, guanidino kinase, mitochondrial permeability transition, octamer stability
Deposited on 1999-07-08, released 2000-04-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: creatine kinase, ubiquitous mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GENBANK ACCESSION J04469 GENE: GENBANK ACCESSION J04469
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qk1a1, d1qk1a2
  • Chain 'B':
    Compound: creatine kinase, ubiquitous mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GENBANK ACCESSION J04469 GENE: GENBANK ACCESSION J04469
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qk1b1, d1qk1b2
  • Chain 'C':
    Compound: creatine kinase, ubiquitous mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GENBANK ACCESSION J04469 GENE: GENBANK ACCESSION J04469
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qk1c1, d1qk1c2
  • Chain 'D':
    Compound: creatine kinase, ubiquitous mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GENBANK ACCESSION J04469 GENE: GENBANK ACCESSION J04469
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qk1d1, d1qk1d2
  • Chain 'E':
    Compound: creatine kinase, ubiquitous mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GENBANK ACCESSION J04469 GENE: GENBANK ACCESSION J04469
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qk1e1, d1qk1e2
  • Chain 'F':
    Compound: creatine kinase, ubiquitous mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GENBANK ACCESSION J04469 GENE: GENBANK ACCESSION J04469
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qk1f1, d1qk1f2
  • Chain 'G':
    Compound: creatine kinase, ubiquitous mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GENBANK ACCESSION J04469 GENE: GENBANK ACCESSION J04469
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qk1g1, d1qk1g2
  • Chain 'H':
    Compound: creatine kinase, ubiquitous mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GENBANK ACCESSION J04469 GENE: GENBANK ACCESSION J04469
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qk1h1, d1qk1h2
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qk1A (A:)
aaserrrlyppsaeypdlrkhnncmashltpavyarlcdkttptgwtldqciqtgvdnpg
hpfiktvgmvagdeetyevfadlfdpviqerhngydprtmkhttdldaskirsgyfdery
vlssrvrtgrsirglslppactraerrevervvvdalsglkgdlagryyrlsemteaeqq
qliddhflfdkpvsplltaagmardwpdargiwhnneksfliwvneedhtrvismekggn
mkrvferfcrglkeverliqergwefmwnerlgyiltcpsnlgtglragvhiklpllskd
srfpkilenlrlqkrgtggvdtaatggvfdisnldrlgksevelvqlvidgvnylidcer
rlergqdiriptpvihtkh

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qk1B (B:)
aaserrrlyppsaeypdlrkhnncmashltpavyarlcdkttptgwtldqciqtgvdnpg
hpfiktvgmvagdeetyevfadlfdpviqerhngydprtmkhttdldaskirsgyfdery
vlssrvrtgrsirglslppactraerrevervvvdalsglkgdlagryyrlsemteaeqq
qliddhflfdkpvsplltaagmardwpdargiwhnneksfliwvneedhtrvismekggn
mkrvferfcrglkeverliqergwefmwnerlgyiltcpsnlgtglragvhiklpllskd
srfpkilenlrlqkrgtggvdtaatggvfdisnldrlgksevelvqlvidgvnylidcer
rlergqdiriptpvihtkh

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qk1C (C:)
aaserrrlyppsaeypdlrkhnncmashltpavyarlcdkttptgwtldqciqtgvdnpg
hpfiktvgmvagdeetyevfadlfdpviqerhngydprtmkhttdldaskirsgyfdery
vlssrvrtgrsirglslppactraerrevervvvdalsglkgdlagryyrlsemteaeqq
qliddhflfdkpvsplltaagmardwpdargiwhnneksfliwvneedhtrvismekggn
mkrvferfcrglkeverliqergwefmwnerlgyiltcpsnlgtglragvhiklpllskd
srfpkilenlrlqkrgtggvdtaatggvfdisnldrlgksevelvqlvidgvnylidcer
rlergqdiriptpvihtkh

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qk1D (D:)
aaserrrlyppsaeypdlrkhnncmashltpavyarlcdkttptgwtldqciqtgvdnpg
hpfiktvgmvagdeetyevfadlfdpviqerhngydprtmkhttdldaskirsgyfdery
vlssrvrtgrsirglslppactraerrevervvvdalsglkgdlagryyrlsemteaeqq
qliddhflfdkpvsplltaagmardwpdargiwhnneksfliwvneedhtrvismekggn
mkrvferfcrglkeverliqergwefmwnerlgyiltcpsnlgtglragvhiklpllskd
srfpkilenlrlqkrgtggvdtaatggvfdisnldrlgksevelvqlvidgvnylidcer
rlergqdiriptpvihtkh

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qk1E (E:)
aaserrrlyppsaeypdlrkhnncmashltpavyarlcdkttptgwtldqciqtgvdnpg
hpfiktvgmvagdeetyevfadlfdpviqerhngydprtmkhttdldaskirsgyfdery
vlssrvrtgrsirglslppactraerrevervvvdalsglkgdlagryyrlsemteaeqq
qliddhflfdkpvsplltaagmardwpdargiwhnneksfliwvneedhtrvismekggn
mkrvferfcrglkeverliqergwefmwnerlgyiltcpsnlgtglragvhiklpllskd
srfpkilenlrlqkrgtggvdtaatggvfdisnldrlgksevelvqlvidgvnylidcer
rlergqdiriptpvihtkh

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qk1F (F:)
aaserrrlyppsaeypdlrkhnncmashltpavyarlcdkttptgwtldqciqtgvdnpg
hpfiktvgmvagdeetyevfadlfdpviqerhngydprtmkhttdldaskirsgyfdery
vlssrvrtgrsirglslppactraerrevervvvdalsglkgdlagryyrlsemteaeqq
qliddhflfdkpvsplltaagmardwpdargiwhnneksfliwvneedhtrvismekggn
mkrvferfcrglkeverliqergwefmwnerlgyiltcpsnlgtglragvhiklpllskd
srfpkilenlrlqkrgtggvdtaatggvfdisnldrlgksevelvqlvidgvnylidcer
rlergqdiriptpvihtkh

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qk1G (G:)
aaserrrlyppsaeypdlrkhnncmashltpavyarlcdkttptgwtldqciqtgvdnpg
hpfiktvgmvagdeetyevfadlfdpviqerhngydprtmkhttdldaskirsgyfdery
vlssrvrtgrsirglslppactraerrevervvvdalsglkgdlagryyrlsemteaeqq
qliddhflfdkpvsplltaagmardwpdargiwhnneksfliwvneedhtrvismekggn
mkrvferfcrglkeverliqergwefmwnerlgyiltcpsnlgtglragvhiklpllskd
srfpkilenlrlqkrgtggvdtaatggvfdisnldrlgksevelvqlvidgvnylidcer
rlergqdiriptpvihtkh

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qk1H (H:)
aaserrrlyppsaeypdlrkhnncmashltpavyarlcdkttptgwtldqciqtgvdnpg
hpfiktvgmvagdeetyevfadlfdpviqerhngydprtmkhttdldaskirsgyfdery
vlssrvrtgrsirglslppactraerrevervvvdalsglkgdlagryyrlsemteaeqq
qliddhflfdkpvsplltaagmardwpdargiwhnneksfliwvneedhtrvismekggn
mkrvferfcrglkeverliqergwefmwnerlgyiltcpsnlgtglragvhiklpllskd
srfpkilenlrlqkrgtggvdtaatggvfdisnldrlgksevelvqlvidgvnylidcer
rlergqdiriptpvihtkh