PDB entry 1qha

View 1qha on RCSB PDB site
Description: human hexokinase type I complexed with ATP analogue amp-pnp
Class: transferase
Keywords: kinase, glycolysis, phosphotransferase, transferase
Deposited on 1999-05-11, released 1999-11-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (hexokinase)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19367
      • conflict (775)
    Domains in SCOPe 2.08: d1qhaa1, d1qhaa2, d1qhaa3, d1qhaa4
  • Chain 'B':
    Compound: protein (hexokinase)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19367
      • conflict (775)
    Domains in SCOPe 2.08: d1qhab1, d1qhab2, d1qhab3, d1qhab4
  • Heterogens: GLC, G6P, MG, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1qhaA (A:)
miaaqllayyftelkddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptat
vkmlptfvrsipdgsekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivh
gsgsqlfdhvaeclgdfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgv
egadvvkllnkaikkrgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacyme
elrhidlvegdegrmcintewgafgddgsledirtefdreidrgslnpgkqlfekmvsgm
ylgelvrlilvkmakegllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlg
vepsdddcvsvqhvctivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykth
pqysrrfhktlrrlvpdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhlt
kdmllevkkrmraemelglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrv
llvkirsgkkrtvemhnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgf
tfsfpcqqtsldagilitwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvg
tmmtcayeeptcevglivgtgsnacymeemknvemvegdqgqmcinmewgafgdngcldd
irthydrlvneyslnagkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrg
ifetkflsqiesdrlallqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaa
vvdkirenrgldrlnvtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkg
aalitavgvrlrteass

    Sequence, based on observed residues (ATOM records): (download) 
    >1qhaA (A:)
telkddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptatvkmlptfvrsi
pdgsekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivhgsgsqlfdhva
eclgdfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgvegadvvkllnk
aikkrgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacymeelrhidlvegd
egrmcintewgafgddgsledirtefdreidrgslnpgkqlfekmvsgmylgelvrlilv
kmakegllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlgvepsdddcvsv
qhvctivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykthpqysrrfhktl
rrlvpdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhltkdmllevkkrm
raemelglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrvllvkirsgkkr
tvemhnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgftfsfpcqqtsl
dagilitwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvgtmmtcayeept
cevglivgtgsnacymeemknvemvegdqgqmcinmewgafgdngclddirthydrlvne
yslnagkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrgifetkflsqie
sdrlallqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaavvdkirenrgl
drlnvtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkgaalitavgvrl
rte

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1qhaB (B:)
miaaqllayyftelkddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptat
vkmlptfvrsipdgsekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivh
gsgsqlfdhvaeclgdfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgv
egadvvkllnkaikkrgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacyme
elrhidlvegdegrmcintewgafgddgsledirtefdreidrgslnpgkqlfekmvsgm
ylgelvrlilvkmakegllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlg
vepsdddcvsvqhvctivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykth
pqysrrfhktlrrlvpdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhlt
kdmllevkkrmraemelglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrv
llvkirsgkkrtvemhnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgf
tfsfpcqqtsldagilitwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvg
tmmtcayeeptcevglivgtgsnacymeemknvemvegdqgqmcinmewgafgdngcldd
irthydrlvneyslnagkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrg
ifetkflsqiesdrlallqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaa
vvdkirenrgldrlnvtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkg
aalitavgvrlrteass

    Sequence, based on observed residues (ATOM records): (download) 
    >1qhaB (B:)
ddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptatvkmlptfvrsipdgs
ekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivhgsgsqlfdhvaeclg
dfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgvegadvvkllnkaikk
rgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacymeelrhidlvegdegrm
cintewgafgddgsledirtefdreidrgslnpgkqlfekmvsgmylgelvrlilvkmak
egllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlgvepsdddcvsvqhvc
tivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykthpqysrrfhktlrrlv
pdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhltkdmllevkkrmraem
elglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrvllvkirsgkkrtvem
hnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgftfsfpcqqtsldagi
litwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvgtmmtcayeeptcevg
livgtgsnacymeemknvemvegdqgqmcinmewgafgdngclddirthydrlvneysln
agkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrgifetkflsqiesdrl
allqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaavvdkirenrgldrln
vtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkgaalitavgvrlrte