SCOPe 2.03: Structural Classification of Proteins

PDB entry 1qbv

View 1qbv on RCSB PDB site
Description: crystal structure of thrombin complexed with an guanidine-mimetic inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: thrombin, inhibitor, 3dp, hydrolase, hydrolase-hydrolase inhibitor complex
Deposited on 1999-04-27, released 1999-10-27
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.193
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

Chain 'E':
Compound: hirudin
Species: Hirudo medicinalis [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Uniprot P28504 (0-10)
Chain 'H':
Compound: thrombin (heavy chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00734 (0-End)
Domains in SCOPe 2.03: d1qbv.1
Chain 'L':
Compound: thrombin (light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00734 (8-21)
Domains in SCOPe 2.03: d1qbv.1
Heterogens: PPX, HOH

PDB Chain Sequences:

Chain 'E':
No sequence available.

Chain 'H':
Sequence, based on SEQRES records: (download)

>1qbvH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

Sequence, based on observed residues (ATOM records): (download)

>1qbvH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlkegqpsvlqvvnlpiverpvckdstriritdnmfca
gykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkk
wiqkvidqf

Chain 'L':
Sequence, based on SEQRES records: (download)
```
>1qbvL (L:)
tfgsgeadcglrplfekksledkterellesyidgr
```
Sequence, based on observed residues (ATOM records): (download)
```
>1qbvL (L:)
adcglrplfekksledkterellesy
```