PDB entry 1q83

View 1q83 on RCSB PDB site
Description: Crystal structure of the mouse acetylcholinesterase-TZ2PA6 syn complex
Class: hydrolase
Keywords: hydrolase, serine esterase, acetylcholinesterase, bifunctional inhibitor
Deposited on 2003-08-20, released 2004-02-10
The last revision prior to the SCOP 1.73 freeze date was dated 2004-02-24, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.183
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: MUS MUSCULUS
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1q83a_
  • Chain 'B':
    Compound: acetylcholinesterase
    Species: MUS MUSCULUS
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1q83b_
  • Heterogens: NAG, P6G, TZ5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1q83A (A:)
mrppwyplhtpslafpllflllsllgggaraegredpqllvrvrggqlrgirlkapggpv
saflgipfaeppvgsrrfmppepkrpwsgvldattfqnvcyqyvdtlypgfegtemwnpn
relsedclylnvwtpyprpasptpvliwiygggfysgaasldvydgrflaqvegavlvsm
nyrvgtfgflalpgsreapgnvglldqrlalqwvqeniaafggdpmsvtlfgesagaasv
gmhilslpsrslfhravlqsgtpngpwatvsagearrratllarlvgcppggaggndtel
iaclrtrpaqdlvdhewhvlpqesifrfsfvpvvdgdflsdtpealintgdfqdlqvlvg
vvkdegsyflvygvpgfskdneslisraqflagvrigvpqasdlaaeavvlhytdwlhpe
dpthlrdamsavvgdhnvvcpvaqlagrlaaqgarvyayifehrastltwplwmgvphgy
eiefifglpldpslnytteerifaqrlmkywtnfartgdpndprdskspqwppyttaaqq
yvslnlkplevrrglraqtcafwnrflpkllsatdtldea

    Sequence, based on observed residues (ATOM records): (download) 
    >1q83A (A:)
egredpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvl
dattfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiyg
ggfysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlal
qwvqeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvs
agearrratllarlvgcpgndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvvdg
dflsdtpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagvri
gvpqasdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqgarv
yayifehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnfar
tgdpndprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpklls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1q83B (B:)
mrppwyplhtpslafpllflllsllgggaraegredpqllvrvrggqlrgirlkapggpv
saflgipfaeppvgsrrfmppepkrpwsgvldattfqnvcyqyvdtlypgfegtemwnpn
relsedclylnvwtpyprpasptpvliwiygggfysgaasldvydgrflaqvegavlvsm
nyrvgtfgflalpgsreapgnvglldqrlalqwvqeniaafggdpmsvtlfgesagaasv
gmhilslpsrslfhravlqsgtpngpwatvsagearrratllarlvgcppggaggndtel
iaclrtrpaqdlvdhewhvlpqesifrfsfvpvvdgdflsdtpealintgdfqdlqvlvg
vvkdegsyflvygvpgfskdneslisraqflagvrigvpqasdlaaeavvlhytdwlhpe
dpthlrdamsavvgdhnvvcpvaqlagrlaaqgarvyayifehrastltwplwmgvphgy
eiefifglpldpslnytteerifaqrlmkywtnfartgdpndprdskspqwppyttaaqq
yvslnlkplevrrglraqtcafwnrflpkllsatdtldea

    Sequence, based on observed residues (ATOM records): (download) 
    >1q83B (B:)
edpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvldat
tfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiygggf
ysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlalqwv
qeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvsage
arrratllarlvgcpndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvvdgdfls
dtpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagvrigvpq
asdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqgarvyayi
fehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnfartgdp
ndprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkll