PDB entry 1q74

View 1q74 on RCSB PDB site
Description: The Crystal Structure of 1D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB)
Class: hydrolase
Keywords: rossmann fold, zinc aminohydrolase, Structural Genomics, PSI, Protein Structure Initiative, TB Structural Genomics Consortium, TBSGC
Deposited on 2003-08-15, released 2003-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-10-27, with a file datestamp of 2009-10-23.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.196
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 1D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB)
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: Rv1170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1q74a_
  • Chain 'B':
    Compound: 1D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB)
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: Rv1170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1q74b_
  • Chain 'C':
    Compound: 1D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB)
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: Rv1170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1q74c_
  • Chain 'D':
    Compound: 1D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB)
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: Rv1170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1q74d_
  • Heterogens: ZN, PE4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1q74A (A:)
msetprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadh
adqlggyrigeltaalralgvsapiylggagrwrdsgmagtdqrsqrrfvdadprqtvga
lvaiirelrphvvvtydpnggyghpdhvhthtvttaavaaagvgsgtadhpgdpwtvpkf
ywtvlglsalisgaralvpddlrpewvlpradeiafgysddgidavveadeqaraakvaa
laahatqvvvgptgraaalsnnlalpiladehyvlaggsagardergwetdllaglgfta
sgt

    Sequence, based on observed residues (ATOM records): (download) 
    >1q74A (A:)
etprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadhad
qlggyrigeltaalralgvsapiylggagrwrdsgmarsqrrfvdadprqtvgalvaiir
elrphvvvtydpnggyghpdhvhthtvttaavaaagvhpgdpwtvpkfywtvlglsalis
garalvpddlrpewvlpradeiafgysddgidavveadeqaraakvaalaahatqvvvgp
tgraaalsnnlalpiladehyvlaggsagardergwetdllaglgft

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1q74B (B:)
msetprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadh
adqlggyrigeltaalralgvsapiylggagrwrdsgmagtdqrsqrrfvdadprqtvga
lvaiirelrphvvvtydpnggyghpdhvhthtvttaavaaagvgsgtadhpgdpwtvpkf
ywtvlglsalisgaralvpddlrpewvlpradeiafgysddgidavveadeqaraakvaa
laahatqvvvgptgraaalsnnlalpiladehyvlaggsagardergwetdllaglgfta
sgt

    Sequence, based on observed residues (ATOM records): (download) 
    >1q74B (B:)
setprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadha
dqlggyrigeltaalralgvsapiylggagrwrdsrsqrrfvdadprqtvgalvaiirel
rphvvvtydpnggyghpdhvhthtvttaavaaagvadhpgdpwtvpkfywtvlglsalis
garalvpddlrpewfgysddgidavveadeqaraakvaalaahatqvvvgptgraaalsn
nlalpiladehyvlaggsagardergwetdllaglgf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1q74C (C:)
msetprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadh
adqlggyrigeltaalralgvsapiylggagrwrdsgmagtdqrsqrrfvdadprqtvga
lvaiirelrphvvvtydpnggyghpdhvhthtvttaavaaagvgsgtadhpgdpwtvpkf
ywtvlglsalisgaralvpddlrpewvlpradeiafgysddgidavveadeqaraakvaa
laahatqvvvgptgraaalsnnlalpiladehyvlaggsagardergwetdllaglgfta
sgt

    Sequence, based on observed residues (ATOM records): (download) 
    >1q74C (C:)
setprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadha
dqlggyrigeltaalralgvsapiylggagrwrdsrsqrrfvdadprqtvgalvaiirel
rphvvvtydpnggyghpdhvhthtvttaavaaagadhpgdpwtvpkfywtvlglsalisg
aralvpddlrpewvlprgysddgidavveadeqaraakvaalaahatqvvvgptgraaal
snnlalpiladehyvlaggsagardergwetdllaglgf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1q74D (D:)
msetprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadh
adqlggyrigeltaalralgvsapiylggagrwrdsgmagtdqrsqrrfvdadprqtvga
lvaiirelrphvvvtydpnggyghpdhvhthtvttaavaaagvgsgtadhpgdpwtvpkf
ywtvlglsalisgaralvpddlrpewvlpradeiafgysddgidavveadeqaraakvaa
laahatqvvvgptgraaalsnnlalpiladehyvlaggsagardergwetdllaglgfta
sgt

    Sequence, based on observed residues (ATOM records): (download) 
    >1q74D (D:)
setprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadha
dqlggyrigeltaalralgvsapiylggagrwrdsgmaqrsqrrfvdadprqtvgalvai
irelrphvvvtydpnggyghpdhvhthtvttaavaaagvadhpgdpwtvpkfywtvlgls
alisgaralvpddlrpgysddgidavveadeqaraakvaalaahatqvvvgptgraaals
nnlalpiladehyvlaggsagardergwetdllaglgf