PDB entry 1q5k

View 1q5k on RCSB PDB site
Description: crystal structure of Glycogen synthase kinase 3 in complexed with inhibitor
Class: transferase
Keywords: kinase-inhibitor complex, TRANSFERASE
Deposited on 2003-08-08, released 2004-08-10
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.222
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1q5ka_
  • Chain 'B':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1q5kb_
  • Heterogens: TMU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1q5kA (A:)
ttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngs
fgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffyssgekkdev
ylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfgichrdikpqn
llldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssidvwsagcv
laelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqikahpwtkvfr
prtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpalfnfttqe
lssnpplatilipphariqaaastptnataasdantgdrgqtnnaasasasnst

    Sequence, based on observed residues (ATOM records): (download) 
    >1q5kA (A:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffysskkdevylnlvldyvpetvyrvarhysrakqtlpvi
yvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsy
icsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtp
treqiremnpefkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleacahsf
fdelrdpnvklpngrdtpalfnfttqelssnpplatilipphari

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1q5kB (B:)
ttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngs
fgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffyssgekkdev
ylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfgichrdikpqn
llldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssidvwsagcv
laelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqikahpwtkvfr
prtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpalfnfttqe
lssnpplatilipphariqaaastptnataasdantgdrgqtnnaasasasnst

    Sequence, based on observed residues (ATOM records): (download) 
    >1q5kB (B:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlp
viyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnv
syicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlg
tptreqiremnpefkfpahpwtkvfrprtppeaialcsrlleytptarltpleacahsff
delrdpnvklpngrdtpalfnfttqelssnpplatilipphari