PDB entry 1q5c

View 1q5c on RCSB PDB site
Description: S-S-lambda-shaped TRANS and CIS interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography
Class: structural protein
Keywords: cadherin; trans interaction; desmosome; junction; adhesion, structural protein
Deposited on 2003-08-06, released 2003-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: EM
Resolution: 30 Å
R-factor: N/A
AEROSPACI score: -0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: EP-cadherin
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1Q5C
    Domains in SCOPe 2.08: d1q5ca_
  • Chain 'B':
    Compound: EP-cadherin
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1Q5C
    Domains in SCOPe 2.08: d1q5cb_
  • Chain 'C':
    Compound: EP-cadherin
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1Q5C
    Domains in SCOPe 2.08: d1q5cc_
  • Chain 'D':
    Compound: EP-cadherin
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1Q5C
    Domains in SCOPe 2.08: d1q5cd_
  • Heterogens: NAG, NDG, CA

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1q5cA (A:)
mgstrlrnasvwlcgllcllqvvpsinadvsgckpgfssaeyifsvnrrelergrklgkv
nfsdcttrkhglydvgdsrfrvlpdgtvlvkrhvklhkdtkftistwdargikhstniav
askrhrsgeeahsrssklpvltfpethtglkrkkrdwvippikvsenergpfpkrlvqik
snkdrfnkvyysitgqgadnppqgvfriewetgwmlvtrpldreeydkyvlsshavseng
spveepmeitinvidqndnrpkftqdvfrgsvregvqpgtqvmavsatdeddnidslngv
lsysilkqdpeepipnlftinretgvisligtgldrekfpeytltvqatdlegaglsveg
kaiiqitdandnapifdpktytalvpeneigfevqrlsvtdldmpgtpawqavykirvne
ggffnittdpesnqgilttakgldfelrkqyvlqitvenaepfsvplptstatvtvtved
vneapffvpavsrvdvsedlsrgekiislvaqdpdkqqiqklsyfigndparwltvnkdn
givtgngnldreseyvknntytvimlvtddgvsvgtgtgtlilhvldvndngpvpsprvf
tmcdqnpepqvltisdadippntypykvslshgsdltwkaeldskgtsmllsptqqlkkg
dysiyvllsdaqnnpqltvvnatvcscegkaikcqeklvggfdlpiilvilgsvlallil
flllllflkrkkvvkeplllpeddtrdnifyygeegggeedqdydlsqlhrgldsrpdim
rndvvptlmpaphyrprpsnpdeignfidenldaadndptappydsllvfdyegsgseaa
slsslnssnsndehdynylsdwgsrfrkladmyggdddee

    Sequence, based on observed residues (ATOM records): (download) 
    >1q5cA (A:)
dwvippikvsenergpfpkrlvqiksnkdrfnkvyysitgqgadnppqgvfriewetgwm
lvtrpldreeydkyvlsshavsengspveepmeitinvidqndnrpkftqdvfrgsvreg
vqpgtqvmavsatdeddnidslngvlsysilkqdpeepipnlftinretgvisligtgld
rekfpeytltvqatdlegaglsvegkaiiqitdandnapifdpktytalvpeneigfevq
rlsvtdldmpgtpawqavykirvneggffnittdpesnqgilttakgldfelrkqyvlqi
tvenaepfsvplptstatvtvtvedvneapffvpavsrvdvsedlsrgekiislvaqdpd
kqqiqklsyfigndparwltvnkdngivtgngnldreseyvknntytvimlvtddgvsvg
tgtgtlilhvldvndngpvpsprvftmcdqnpepqvltisdadippntypykvslshgsd
ltwkaeldskgtsmllsptqqlkkgdysiyvllsdaqnnpqltvvnatvcscegkaikcq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1q5cB (B:)
mgstrlrnasvwlcgllcllqvvpsinadvsgckpgfssaeyifsvnrrelergrklgkv
nfsdcttrkhglydvgdsrfrvlpdgtvlvkrhvklhkdtkftistwdargikhstniav
askrhrsgeeahsrssklpvltfpethtglkrkkrdwvippikvsenergpfpkrlvqik
snkdrfnkvyysitgqgadnppqgvfriewetgwmlvtrpldreeydkyvlsshavseng
spveepmeitinvidqndnrpkftqdvfrgsvregvqpgtqvmavsatdeddnidslngv
lsysilkqdpeepipnlftinretgvisligtgldrekfpeytltvqatdlegaglsveg
kaiiqitdandnapifdpktytalvpeneigfevqrlsvtdldmpgtpawqavykirvne
ggffnittdpesnqgilttakgldfelrkqyvlqitvenaepfsvplptstatvtvtved
vneapffvpavsrvdvsedlsrgekiislvaqdpdkqqiqklsyfigndparwltvnkdn
givtgngnldreseyvknntytvimlvtddgvsvgtgtgtlilhvldvndngpvpsprvf
tmcdqnpepqvltisdadippntypykvslshgsdltwkaeldskgtsmllsptqqlkkg
dysiyvllsdaqnnpqltvvnatvcscegkaikcqeklvggfdlpiilvilgsvlallil
flllllflkrkkvvkeplllpeddtrdnifyygeegggeedqdydlsqlhrgldsrpdim
rndvvptlmpaphyrprpsnpdeignfidenldaadndptappydsllvfdyegsgseaa
slsslnssnsndehdynylsdwgsrfrkladmyggdddee

    Sequence, based on observed residues (ATOM records): (download) 
    >1q5cB (B:)
dwvippikvsenergpfpkrlvqiksnkdrfnkvyysitgqgadnppqgvfriewetgwm
lvtrpldreeydkyvlsshavsengspveepmeitinvidqndnrpkftqdvfrgsvreg
vqpgtqvmavsatdeddnidslngvlsysilkqdpeepipnlftinretgvisligtgld
rekfpeytltvqatdlegaglsvegkaiiqitdandnapifdpktytalvpeneigfevq
rlsvtdldmpgtpawqavykirvneggffnittdpesnqgilttakgldfelrkqyvlqi
tvenaepfsvplptstatvtvtvedvneapffvpavsrvdvsedlsrgekiislvaqdpd
kqqiqklsyfigndparwltvnkdngivtgngnldreseyvknntytvimlvtddgvsvg
tgtgtlilhvldvndngpvpsprvftmcdqnpepqvltisdadippntypykvslshgsd
ltwkaeldskgtsmllsptqqlkkgdysiyvllsdaqnnpqltvvnatvcscegkaikcq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1q5cC (C:)
mgstrlrnasvwlcgllcllqvvpsinadvsgckpgfssaeyifsvnrrelergrklgkv
nfsdcttrkhglydvgdsrfrvlpdgtvlvkrhvklhkdtkftistwdargikhstniav
askrhrsgeeahsrssklpvltfpethtglkrkkrdwvippikvsenergpfpkrlvqik
snkdrfnkvyysitgqgadnppqgvfriewetgwmlvtrpldreeydkyvlsshavseng
spveepmeitinvidqndnrpkftqdvfrgsvregvqpgtqvmavsatdeddnidslngv
lsysilkqdpeepipnlftinretgvisligtgldrekfpeytltvqatdlegaglsveg
kaiiqitdandnapifdpktytalvpeneigfevqrlsvtdldmpgtpawqavykirvne
ggffnittdpesnqgilttakgldfelrkqyvlqitvenaepfsvplptstatvtvtved
vneapffvpavsrvdvsedlsrgekiislvaqdpdkqqiqklsyfigndparwltvnkdn
givtgngnldreseyvknntytvimlvtddgvsvgtgtgtlilhvldvndngpvpsprvf
tmcdqnpepqvltisdadippntypykvslshgsdltwkaeldskgtsmllsptqqlkkg
dysiyvllsdaqnnpqltvvnatvcscegkaikcqeklvggfdlpiilvilgsvlallil
flllllflkrkkvvkeplllpeddtrdnifyygeegggeedqdydlsqlhrgldsrpdim
rndvvptlmpaphyrprpsnpdeignfidenldaadndptappydsllvfdyegsgseaa
slsslnssnsndehdynylsdwgsrfrkladmyggdddee

    Sequence, based on observed residues (ATOM records): (download) 
    >1q5cC (C:)
dwvippikvsenergpfpkrlvqiksnkdrfnkvyysitgqgadnppqgvfriewetgwm
lvtrpldreeydkyvlsshavsengspveepmeitinvidqndnrpkftqdvfrgsvreg
vqpgtqvmavsatdeddnidslngvlsysilkqdpeepipnlftinretgvisligtgld
rekfpeytltvqatdlegaglsvegkaiiqitdandnapifdpktytalvpeneigfevq
rlsvtdldmpgtpawqavykirvneggffnittdpesnqgilttakgldfelrkqyvlqi
tvenaepfsvplptstatvtvtvedvneapffvpavsrvdvsedlsrgekiislvaqdpd
kqqiqklsyfigndparwltvnkdngivtgngnldreseyvknntytvimlvtddgvsvg
tgtgtlilhvldvndngpvpsprvftmcdqnpepqvltisdadippntypykvslshgsd
ltwkaeldskgtsmllsptqqlkkgdysiyvllsdaqnnpqltvvnatvcscegkaikcq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1q5cD (D:)
mgstrlrnasvwlcgllcllqvvpsinadvsgckpgfssaeyifsvnrrelergrklgkv
nfsdcttrkhglydvgdsrfrvlpdgtvlvkrhvklhkdtkftistwdargikhstniav
askrhrsgeeahsrssklpvltfpethtglkrkkrdwvippikvsenergpfpkrlvqik
snkdrfnkvyysitgqgadnppqgvfriewetgwmlvtrpldreeydkyvlsshavseng
spveepmeitinvidqndnrpkftqdvfrgsvregvqpgtqvmavsatdeddnidslngv
lsysilkqdpeepipnlftinretgvisligtgldrekfpeytltvqatdlegaglsveg
kaiiqitdandnapifdpktytalvpeneigfevqrlsvtdldmpgtpawqavykirvne
ggffnittdpesnqgilttakgldfelrkqyvlqitvenaepfsvplptstatvtvtved
vneapffvpavsrvdvsedlsrgekiislvaqdpdkqqiqklsyfigndparwltvnkdn
givtgngnldreseyvknntytvimlvtddgvsvgtgtgtlilhvldvndngpvpsprvf
tmcdqnpepqvltisdadippntypykvslshgsdltwkaeldskgtsmllsptqqlkkg
dysiyvllsdaqnnpqltvvnatvcscegkaikcqeklvggfdlpiilvilgsvlallil
flllllflkrkkvvkeplllpeddtrdnifyygeegggeedqdydlsqlhrgldsrpdim
rndvvptlmpaphyrprpsnpdeignfidenldaadndptappydsllvfdyegsgseaa
slsslnssnsndehdynylsdwgsrfrkladmyggdddee

    Sequence, based on observed residues (ATOM records): (download) 
    >1q5cD (D:)
dwvippikvsenergpfpkrlvqiksnkdrfnkvyysitgqgadnppqgvfriewetgwm
lvtrpldreeydkyvlsshavsengspveepmeitinvidqndnrpkftqdvfrgsvreg
vqpgtqvmavsatdeddnidslngvlsysilkqdpeepipnlftinretgvisligtgld
rekfpeytltvqatdlegaglsvegkaiiqitdandnapifdpktytalvpeneigfevq
rlsvtdldmpgtpawqavykirvneggffnittdpesnqgilttakgldfelrkqyvlqi
tvenaepfsvplptstatvtvtvedvneapffvpavsrvdvsedlsrgekiislvaqdpd
kqqiqklsyfigndparwltvnkdngivtgngnldreseyvknntytvimlvtddgvsvg
tgtgtlilhvldvndngpvpsprvftmcdqnpepqvltisdadippntypykvslshgsd
ltwkaeldskgtsmllsptqqlkkgdysiyvllsdaqnnpqltvvnatvcscegkaikcq