PDB entry 1py2

View 1py2 on RCSB PDB site
Description: Structure of a 60 nM Small Molecule Bound to a Hot Spot on IL-2
Class: immune system
Keywords: IL-2, interleukin 2, small molecule, hot spot, molecular recognition, IMMUNE SYSTEM
Deposited on 2003-07-07, released 2004-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.273
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1py2a_
  • Chain 'B':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1py2b_
  • Chain 'C':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1py2c_
  • Chain 'D':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1py2d_
  • Heterogens: ZN, FRH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1py2A (A:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistl

    Sequence, based on observed residues (ATOM records): (download) 
    >1py2A (A:)
stkktqlqlehllldlqmilnginnypkltrmltfkfympkkatelkhlqcleeelkple
evlnlafrprdlisninvivlelkettfmceyadetativeflnrwitfcqsiistl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1py2B (B:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistl

    Sequence, based on observed residues (ATOM records): (download) 
    >1py2B (B:)
stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
leevlnlaqrprdlisninvivlelkfmceyadetativeflnrwitfcqsiistl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1py2C (C:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistl

    Sequence, based on observed residues (ATOM records): (download) 
    >1py2C (C:)
tkktqlqlehllldlqmilnginnykkltrmltfkfympkkatelkhlqcleeelkplee
vlnlaqprdlisninvivlelkgettfmceyadetativeflnrwitfcqsiist

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1py2D (D:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistl

    Sequence, based on observed residues (ATOM records): (download) 
    >1py2D (D:)
stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
leevlnlaqrprdlisninvivlelkgettfmceyadetativeflnrwitfcqsiistl