PDB entry 1px6

View 1px6 on RCSB PDB site
Description: A folding mutant of human class pi glutathione transferase, created by mutating aspartate 153 of the wild-type protein to asparagine
Class: transferase
Keywords: glutathione transferase, helix capping, mutations, protein folding, X-ray crystallography
Deposited on 2003-07-02, released 2003-07-22
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.19
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione S-transferase P
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09211 (0-208)
      • engineered (151)
    Domains in SCOPe 2.04: d1px6a1, d1px6a2
  • Chain 'B':
    Compound: Glutathione S-transferase P
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09211 (0-208)
      • engineered (151)
    Domains in SCOPe 2.04: d1px6b1, d1px6b2
  • Heterogens: MES, GSH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1px6A (A:)
ppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgdl
tlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvk
alpgqlkpfetllsqnqggktfivgdqisfanynlldlllihevlapgcldafpllsayv
grlsarpklkaflaspeyvnlpingngkq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1px6B (B:)
ppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgdl
tlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvk
alpgqlkpfetllsqnqggktfivgdqisfanynlldlllihevlapgcldafpllsayv
grlsarpklkaflaspeyvnlpingngkq