PDB entry 1pw6

View 1pw6 on RCSB PDB site
Description: Low Micromolar Small Molecule Inhibitor of IL-2
Class: immune system
Keywords: IL-2 interleukin 2 small molecule inhibitor, IMMUNE SYSTEM
Deposited on 2003-06-30, released 2004-01-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.259
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1pw6a_
  • Chain 'B':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1pw6b_
  • Heterogens: SO4, FRB

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pw6A (A:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >1pw6A (A:)
stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
leevlnlaqrprdlisninvivlelkgsettfmceyadetativeflnrwitfcqsiist
l

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pw6B (B:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >1pw6B (B:)
sstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelk
pleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrwitf
cqsiistlt