PDB entry 1pu5

View 1pu5 on RCSB PDB site
Description: GM2-activator Protein crystal structure
Class: lipid binding protein
Keywords: Beta cup, large lipid binding pocket, protein dynamics
Deposited on 2003-06-24, released 2004-06-29
The last revision prior to the SCOP 1.73 freeze date was dated 2004-06-29, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.214
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ganglioside GM2 activator
    Species: HOMO SAPIENS
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • cloning artifact (0-1)
    Domains in SCOP 1.73: d1pu5a_
  • Chain 'B':
    Compound: Ganglioside GM2 activator
    Species: HOMO SAPIENS
    Gene: GM2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17900 (2-163)
      • cloning artifact (0-1)
    Domains in SCOP 1.73: d1pu5b_
  • Chain 'C':
    Compound: Ganglioside GM2 activator
    Species: HOMO SAPIENS
    Gene: GM2A
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1pu5c_
  • Heterogens: EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1pu5A (A:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1pu5B (B:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1pu5C (C:)
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

    Sequence, based on observed residues (ATOM records): (download) 
    >1pu5C (C:)
sfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvlekevag
lwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpksef
vvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi