SCOPe 2.05: Structural Classification of Proteins

PDB entry 1pqu

View 1pqu on RCSB PDB site
Description: Crystal Structure of the H277N Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae Bound with NADP, S-methyl cysteine sulfoxide and cacodylate
Class: oxidoreductase
Keywords: Enzyme, L-aspartate semialdehyde, cacodylate, NADP, OXIDOREDUCTASE
Deposited on 2003-06-19, released 2004-08-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: 0.182
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: aspartate-semialdehyde dehydrogenase
Species: HAEMOPHILUS INFLUENZAE [TaxId:71421]
Gene: ASD
Database cross-references and differences (RAF-indexed):
- Uniprot P44801 (0-370)
  - engineered (276)
Domains in SCOPe 2.05: d1pqua1, d1pqua2
Chain 'B':
Compound: aspartate-semialdehyde dehydrogenase
Species: HAEMOPHILUS INFLUENZAE [TaxId:71421]
Gene: ASD
Database cross-references and differences (RAF-indexed):
- Uniprot P44801 (0-370)
  - engineered (276)
Domains in SCOPe 2.05: d1pqub1, d1pqub2
Chain 'C':
Compound: aspartate-semialdehyde dehydrogenase
Species: HAEMOPHILUS INFLUENZAE [TaxId:71421]
Gene: ASD
Database cross-references and differences (RAF-indexed):
- Uniprot P44801 (0-370)
  - engineered (276)
Domains in SCOPe 2.05: d1pquc1, d1pquc2
Chain 'D':
Compound: aspartate-semialdehyde dehydrogenase
Species: HAEMOPHILUS INFLUENZAE [TaxId:71421]
Gene: ASD
Database cross-references and differences (RAF-indexed):
- Uniprot P44801 (0-370)
  - engineered (276)
Domains in SCOPe 2.05: d1pqud1, d1pqud2
Heterogens: CAC, NAP, CYS, HOH

PDB Chain Sequences:

Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)

>1pquA (A:)
mknvgfigwrgmvgsvlmdrmsqendfenlnpvffttsqagqkapvfggkdagdlksafd
ieelkkldiivtcqggdytnevypklkatgwdgywvdaasalrmkddaiivldpvnqhvi
seglkkgiktfvggnctvslmlmaigglfekdlvewisvatyqaasgagaknmrellsqm
glleqavsselkdpassildierkvtakmradnfptdnfgaalggslipwidkllpetgq
tkeewkgyaetnkilglsdnpipvdglcvrigalrcnsqaftiklkkdlpleeieqiias
hnewvkvipndkeitlreltpakvtgtlsvpvgrlrklamgpeylaaftvgdqllwgaae
pvrrilkqlva

Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)

>1pquB (B:)
mknvgfigwrgmvgsvlmdrmsqendfenlnpvffttsqagqkapvfggkdagdlksafd
ieelkkldiivtcqggdytnevypklkatgwdgywvdaasalrmkddaiivldpvnqhvi
seglkkgiktfvggnctvslmlmaigglfekdlvewisvatyqaasgagaknmrellsqm
glleqavsselkdpassildierkvtakmradnfptdnfgaalggslipwidkllpetgq
tkeewkgyaetnkilglsdnpipvdglcvrigalrcnsqaftiklkkdlpleeieqiias
hnewvkvipndkeitlreltpakvtgtlsvpvgrlrklamgpeylaaftvgdqllwgaae
pvrrilkqlva

Chain 'C':
Sequence, based on SEQRES records: (download)

>1pquC (C:)
mknvgfigwrgmvgsvlmdrmsqendfenlnpvffttsqagqkapvfggkdagdlksafd
ieelkkldiivtcqggdytnevypklkatgwdgywvdaasalrmkddaiivldpvnqhvi
seglkkgiktfvggnctvslmlmaigglfekdlvewisvatyqaasgagaknmrellsqm
glleqavsselkdpassildierkvtakmradnfptdnfgaalggslipwidkllpetgq
tkeewkgyaetnkilglsdnpipvdglcvrigalrcnsqaftiklkkdlpleeieqiias
hnewvkvipndkeitlreltpakvtgtlsvpvgrlrklamgpeylaaftvgdqllwgaae
pvrrilkqlva

Sequence, based on observed residues (ATOM records): (download)

>1pquC (C:)
mknvgfigwrgmvgsvlmdrmsqendfenlnpvffttsqlksafdieelkkldiivtcqg
gdytnevypklkatgwdgywvdaasalrmkddaiivldpvnqhviseglkkgiktfvggn
ctvslmlmaigglfekdlvewisvatyqaasgagaknmrellsqmglleqavsselkdpa
ssildierkvtakmradnfptdnfgaalggslipwidkllpetgqtkeewkgyaetnkil
glsdnpipvdglcvrigalrcnsqaftiklkkdlpleeieqiiashnewvkvipndkeit
lreltpakvtgtlsvpvgrlrklamgpeylaaftvgdqllwgaaepvrrilkqlva

Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)

>1pquD (D:)
mknvgfigwrgmvgsvlmdrmsqendfenlnpvffttsqagqkapvfggkdagdlksafd
ieelkkldiivtcqggdytnevypklkatgwdgywvdaasalrmkddaiivldpvnqhvi
seglkkgiktfvggnctvslmlmaigglfekdlvewisvatyqaasgagaknmrellsqm
glleqavsselkdpassildierkvtakmradnfptdnfgaalggslipwidkllpetgq
tkeewkgyaetnkilglsdnpipvdglcvrigalrcnsqaftiklkkdlpleeieqiias
hnewvkvipndkeitlreltpakvtgtlsvpvgrlrklamgpeylaaftvgdqllwgaae
pvrrilkqlva