PDB entry 1po2

View 1po2 on RCSB PDB site
Description: poliovirus (type 1, mahoney) in complex with r77975, an inhibitor of viral replication
Class: virus
Keywords: POLIOVIRUS, PICORNAVIRUS COAT PROTEIN, ANTI-VIRAL DRUGS, HYDROLASE, THIOL PROTEASE, Icosahedral virus, Virus
Deposited on 1997-01-08, released 1997-12-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-29, with a file datestamp of 2017-11-24.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '0':
    Compound: poliovirus type 1 mahoney
    Species: Human poliovirus 1 [TaxId:12081]
    Database cross-references and differences (RAF-indexed):
    • PDB 1PO2 (0-4)
  • Chain '1':
    Compound: poliovirus type 1 mahoney
    Species: Human poliovirus 1 [TaxId:12081]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1po21_
  • Chain '2':
    Compound: poliovirus type 1 mahoney
    Species: Human poliovirus 1 [TaxId:12081]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1po2.1
  • Chain '3':
    Compound: poliovirus type 1 mahoney
    Species: Human poliovirus 1 [TaxId:12081]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03300 (0-End)
      • conflict (122)
    Domains in SCOPe 2.08: d1po23_
  • Chain '4':
    Compound: poliovirus type 1 mahoney
    Species: Human poliovirus 1 [TaxId:12081]
    Database cross-references and differences (RAF-indexed):
    • PDB 1PO2 (0-67)
    Domains in SCOPe 2.08: d1po2.1
  • Heterogens: J77, MYR

PDB Chain Sequences:

  • Chain '0':
    No sequence available.

  • Chain '1':
    Sequence, based on SEQRES records: (download) 
    >1po21 (1:)
glgqmlesmidntvretvgaatsrdalpnteasgpthskeipaltavetgatnplvpsdt
vqtrhvvqhrsrsessiesffargacvtimtvdnpasttnkdklfavwkitykdtvqlrr
klefftysrfdmeltfvvtanftetnnghalnqvyqimyvppgapvpekwddytwqtssn
psifytygtaparisvpyvgisnayshfydgfskvplkdqsaalgdslygaaslndfgil
avrvvndhnptkvtskirvylkpkhirvwcprppravayygpgvdykdgtltplstkdlt
ty

    Sequence, based on observed residues (ATOM records): (download) 
    >1po21 (1:)
aatsrdalpnteasgpthskeipaltavetgatnplvpsdtvqtrhvvqhrsrsessies
ffargacvtimtvdnpasttnkdklfavwkitykdtvqlrrklefftysrfdmeltfvvt
anftetnnghalnqvyqimyvppgapvpekwddytwqtssnpsifytygtaparisvpyv
gisnayshfydgfskvplkdqsaalgdslygaaslndfgilavrvvndhnptkvtskirv
ylkpkhirvwcprppravayygpgvdykdgtltplstkdltty

  • Chain '2':
    Sequence, based on SEQRES records: (download) 
    >1po22 (2:)
spnieacgysdrvlqltlgnstittqeaansvvaygrwpeylrdseanpvdqptepdvaa
crfytldtvswtkesrgwwwklpdalrdmglfgqnmyyhylgrsgytvhvqcnaskfhqg
algvfavpemclagdsntttmhtsyqnanpgekggtftgtftpdnnqtsparrfcpvdyl
lgngtllgnafvfphqiinlrtnncatlvlpyvnslsidsmvkhnnwgiailplaplnfa
sesspeipitltiapmccefnglrnitlprlq

    Sequence, based on observed residues (ATOM records): (download) 
    >1po22 (2:)
eacgysdrvlqltlgnstittqeaansvvaygrwpeylrdseanpvdqptepdvaacrfy
tldtvswtkesrgwwwklpdalrdmglfgqnmyyhylgrsgytvhvqcnaskfhqgalgv
favpemclagdsntttmhtsyqnanpgekggtftgtftpdnnqtsparrfcpvdyllgng
tllgnafvfphqiinlrtnncatlvlpyvnslsidsmvkhnnwgiailplaplnfasess
peipitltiapmccefnglrnitlprlq

  • Chain '3':
    Sequence, based on SEQRES records: (download) 
    >1po23 (3:)
glpvmntpgsnqyltadnfqspcalpefdvtppidipgevknmmelaeidtmipfdlsat
kkntmemyrvrlsdkphtddpilclslspasdprlshtmlgeilnyythwagslkftflf
cgsmmatgkllvsyappgadppkkrkeamlgthviwdiglqssctmvvpwisnttyrqti
ddsfteggyisvfyqtrivvplstpremdilgfvsacndfsvrllrdtthieqkalaq

    Sequence, based on observed residues (ATOM records): (download) 
    >1po23 (3:)
glpvmntpgsnqyltadnfqspcalpefdvtppidipgevknmmelaeidtmipfdlsat
kkntmemyrvrlsdkphtddpilclslspasdprlshtmlgeilnyythwagslkftflf
cgsmmatgkllvsyappgadppkkrkeamlgthviwdiglqssctmvvpwisnttyrqti
ddsfteggyisvfyqtrivvplstpremdilgfvsacndfsvrllrdtthieqka

  • Chain '4':
    Sequence, based on SEQRES records: (download) 
    >1po24 (4:)
gaqvssqkvgahensnrayggstinyttinyyrdsasnaaskqdfsqdpskftepikdvl
iktapmln

    Sequence, based on observed residues (ATOM records): (download) 
    >1po24 (4:)
gaqvssqkvgahensstinyttinyyrdsasnaaskqdfsqdpskftepikdvliktapm
ln