PDB entry 1pn3

View 1pn3 on RCSB PDB site
Description: Crystal Structure of TDP-epi-Vancosaminyltransferase GtfA in complexes with TDP and the acceptor substrate DVV.
Class: transferase/antibiotic
Keywords: gt-b glycosyltransferase, rossmann fold, glycopeptide, vancomycin, antibiotic, transferase-antibiotic complex
Deposited on 2003-06-12, released 2003-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glycosyltransferase gtfa
    Species: AMYCOLATOPSIS ORIENTALIS [TaxId:31958]
    Gene: gtfA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96558 (0-End)
    • PDB 1PN3
    Domains in SCOPe 2.08: d1pn3a_
  • Chain 'B':
    Compound: glycosyltransferase gtfa
    Species: AMYCOLATOPSIS ORIENTALIS [TaxId:31958]
    Gene: gtfA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96558 (0-End)
    • PDB 1PN3
    Domains in SCOPe 2.08: d1pn3b_
  • Chain 'C':
    Compound: desvancosaminyl vancomycin
    Species: AMYCOLATOPSIS ORIENTALIS [TaxId:31958]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00681 (0-6)
  • Chain 'D':
    Compound: desvancosaminyl vancomycin
    Species: AMYCOLATOPSIS ORIENTALIS [TaxId:31958]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00681 (0-6)
  • Heterogens: TYD, BGC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pn3A (A:)
mrvlitgcgsrgdteplvalaarlrelgadarmclppdyvercaevgvpmvpvgravrag
arepgelppgaaevvtevvaewfdkvpaaiegcdavvttgllpaavavrsmaeklgipyr
ytvlspdhlpseqsqaerdmynqgadrlfgdavnshrasiglppvehlydygytdqpwla
adpvlsplrptdlgtvqtgawilpderplsaeleaflaagstpvyvgfgsssrpatadaa
kmaikavrasgrrivlsrgwadlvlpddgadcfvvgevnlqelfgrvaaaihhdsagttl
lamragipqivvrrvvdnvveqayhadrvaelgvgvavdgpvptidslsaaldtalapei
rarattvadtiradgttvaaqllfdavslekptvpalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1pn3A (A:)
mrvlitgcgsrgdteplvalaarlrelgadarmclppdyvercaevgvpmvpvgravrag
arepgelppgaaevvtevvaewfdkvpaaiegcdavvttgllpaavavrsmaeklgipyr
ytvlspdhlpseqsqaerdmynqgadrlfgdavnshrasiglppvehlydygytdqpwla
adpvlsplrptdlgtvqtgawilpderplsaeleaflaagstpvyvgfgsssrpatadaa
kmaikavrasgrrivlsrgwadlvlpddgadcfvvgevnlqelfgrvaaaihhdsagttl
lamragipqivvrrvvdnvveqayhadrvaelgvgvavdgpvptidslsaaldtalapei
rarattvadtiradgttvaaqllfdavslek

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pn3B (B:)
mrvlitgcgsrgdteplvalaarlrelgadarmclppdyvercaevgvpmvpvgravrag
arepgelppgaaevvtevvaewfdkvpaaiegcdavvttgllpaavavrsmaeklgipyr
ytvlspdhlpseqsqaerdmynqgadrlfgdavnshrasiglppvehlydygytdqpwla
adpvlsplrptdlgtvqtgawilpderplsaeleaflaagstpvyvgfgsssrpatadaa
kmaikavrasgrrivlsrgwadlvlpddgadcfvvgevnlqelfgrvaaaihhdsagttl
lamragipqivvrrvvdnvveqayhadrvaelgvgvavdgpvptidslsaaldtalapei
rarattvadtiradgttvaaqllfdavslekptvpalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1pn3B (B:)
mrvlitgcgsrgdteplvalaarlrelgadarmclppdyvercaevgvpmvpvgravrag
arepgelppgaaevvtevvaewfdkvpaaiegcdavvttgllpaavavrsmaeklgipyr
ytvlspdhlpseqsqaerdmynqgadrlfgdavnshrasiglppvehlydygytdqpwla
adpvlsplrptdlgtvqtgawilpderplsaeleaflaagstpvyvgfgsssrpatadaa
kmaikavrasgrrivlsrgwadlvlpddgadcfvvgevnlqelfgrvaaaihhdsagttl
lamragipqivvrrvayhadrvaelgvgvavdgpvptidslsaaldtalapeirarattv
adtiradgttvaaqllfdavslek

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.