PDB entry 1pn2

View 1pn2 on RCSB PDB site
Description: Crystal structure analysis of the selenomethionine labelled 2-enoyl-CoA hydratase 2 domain of Candida tropicalis multifunctional enzyme type 2
Class: lyase
Keywords: hot-dog fold, hydratase 2 motif, lyase
Deposited on 2003-06-12, released 2004-04-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.182
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisomal hydratase-dehydrogenase-epimerase
    Species: Candida tropicalis [TaxId:5482]
    Gene: FOX2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22414
      • modified residue (68)
      • modified residue (205)
      • modified residue (221)
    Domains in SCOPe 2.08: d1pn2a1, d1pn2a2
  • Chain 'B':
    Compound: Peroxisomal hydratase-dehydrogenase-epimerase
    Species: Candida tropicalis [TaxId:5482]
    Gene: FOX2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22414
      • modified residue (68)
      • modified residue (205)
      • modified residue (221)
    Domains in SCOPe 2.08: d1pn2b1, d1pn2b2
  • Chain 'C':
    Compound: Peroxisomal hydratase-dehydrogenase-epimerase
    Species: Candida tropicalis [TaxId:5482]
    Gene: FOX2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22414
      • modified residue (68)
      • modified residue (205)
      • modified residue (221)
    Domains in SCOPe 2.08: d1pn2c1, d1pn2c2
  • Chain 'D':
    Compound: Peroxisomal hydratase-dehydrogenase-epimerase
    Species: Candida tropicalis [TaxId:5482]
    Gene: FOX2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22414
      • modified residue (68)
      • modified residue (205)
      • modified residue (221)
    Domains in SCOPe 2.08: d1pn2d1, d1pn2d2
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pn2A (A:)
meddpvwrfddrdvilynialgattkqlkyvyendsdfqviptfghlitfnsgksqnsfa
kllrnfnpmlllhgehylkvhswppptegeikttfepiattpkgtnvvivhgsksvdnks
geliysneatyfirncqadnkvyadrpafatnqflapkrapdyqvdvpvsedlaalyrls
gdrnplhidpnfakgakfpkpilhgmctyglsakalidkfgmfneikarftgivfpgetl
rvlawkesddtivfqthvvdrgtiainnaaiklvgdkaki

    Sequence, based on observed residues (ATOM records): (download) 
    >1pn2A (A:)
dpvwrfddrdvilynialgattkqlkyvyendsdfqviptfghlitfnsgksqnsfakll
rnfnpmlllhgehylkvhswppptegeikttfepiattpkgtnvvivhgsksvdnksgel
iysneatyfirncqadnkvyadrpafatnqflapkrapdyqvdvpvsedlaalyrlsgdr
nplhidpnfakgakfpkpilhgmctyglsakalidkfgmfneikarftgivfpgetlrvl
awkesddtivfqthvvdrgtiainnaaiklvg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pn2B (B:)
meddpvwrfddrdvilynialgattkqlkyvyendsdfqviptfghlitfnsgksqnsfa
kllrnfnpmlllhgehylkvhswppptegeikttfepiattpkgtnvvivhgsksvdnks
geliysneatyfirncqadnkvyadrpafatnqflapkrapdyqvdvpvsedlaalyrls
gdrnplhidpnfakgakfpkpilhgmctyglsakalidkfgmfneikarftgivfpgetl
rvlawkesddtivfqthvvdrgtiainnaaiklvgdkaki

    Sequence, based on observed residues (ATOM records): (download) 
    >1pn2B (B:)
pvwrfddrdvilynialgattkqlkyvyendsdfqviptfghlitfnsgksqnsfakllr
nfnpmlllhgehylkvhswppptegeikttfepiattpkgtnvvivhgsksvdnksgeli
ysneatyfirncqadnkvyadrpafatnqflapkrapdyqvdvpvsedlaalyrlsgdrn
plhidpnfakgakfpkpilhgmctyglsakalidkfgmfneikarftgivfpgetlrvla
wkesddtivfqthvvdrgtiainnaaiklv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1pn2C (C:)
meddpvwrfddrdvilynialgattkqlkyvyendsdfqviptfghlitfnsgksqnsfa
kllrnfnpmlllhgehylkvhswppptegeikttfepiattpkgtnvvivhgsksvdnks
geliysneatyfirncqadnkvyadrpafatnqflapkrapdyqvdvpvsedlaalyrls
gdrnplhidpnfakgakfpkpilhgmctyglsakalidkfgmfneikarftgivfpgetl
rvlawkesddtivfqthvvdrgtiainnaaiklvgdkaki

    Sequence, based on observed residues (ATOM records): (download) 
    >1pn2C (C:)
pvwrfddrdvilynialgattkqlkyvyendsdfqviptfghlitfnsnsfakllrnfnp
mlllhgehylkvhswppptegeikttfepiattpkgtnvvivhgsksvdnksgeliysne
atyfirncqadnkvyadrpafatnqflapkrapdyqvdvpvsedlaalyrlsgdrnplhi
dpnfakgakfpkpilhgmctyglsakalidkfgmfneikarftgivfpgetlrvlawkes
ddtivfqthvvdrgtiainnaaiklvg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1pn2D (D:)
meddpvwrfddrdvilynialgattkqlkyvyendsdfqviptfghlitfnsgksqnsfa
kllrnfnpmlllhgehylkvhswppptegeikttfepiattpkgtnvvivhgsksvdnks
geliysneatyfirncqadnkvyadrpafatnqflapkrapdyqvdvpvsedlaalyrls
gdrnplhidpnfakgakfpkpilhgmctyglsakalidkfgmfneikarftgivfpgetl
rvlawkesddtivfqthvvdrgtiainnaaiklvgdkaki

    Sequence, based on observed residues (ATOM records): (download) 
    >1pn2D (D:)
pvwrfddrdvilynialgattkqlkyvyendsdfqviptfghlitfnsgksqnsfakllr
nfnpmlllhgehylkvhswppptegeikttfepiattpkgtnvvivhgsksvdnksgeli
ysneatyfirncqadnkvyadrpafatnqflapkrapdyqvdvpvsedlaalyrlsgdrn
plhidpnfakgakfpkpilhgmctyglsakalidkfgmfneikarftgivfpgetlrvla
wkesddtivfqthvvdrgtiainnaaiklvgd