PDB entry 1pkd
View 1pkd on RCSB PDB site
Description: the crystal structure of ucn-01 in complex with phospho-cdk2/cyclin a
Class: transferase/cell cycle
Keywords: Protein kinase-drug complex, TRANSFERASE-CELL CYCLE COMPLEX
Deposited on
2003-06-05, released
2003-06-24
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-01-31, with a file datestamp of
2018-01-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2
Database cross-references and differences (RAF-indexed):
- Uniprot P24941 (1-296)
- cloning artifact (0)
- modified residue (160)
Domains in SCOPe 2.08: d1pkda1, d1pkda2 - Chain 'B':
Compound: cyclin a2
Species: Homo sapiens [TaxId:9606]
Gene: CCNA2 OR CCNA OR CCN1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1pkdb1, d1pkdb2 - Chain 'C':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2
Database cross-references and differences (RAF-indexed):
- Uniprot P24941 (1-296)
- cloning artifact (0)
- modified residue (160)
Domains in SCOPe 2.08: d1pkdc1, d1pkdc2 - Chain 'D':
Compound: cyclin a2
Species: Homo sapiens [TaxId:9606]
Gene: CCNA2 OR CCNA OR CCN1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1pkdd1, d1pkdd2 - Heterogens: UCN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1pkdA (A:)
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1pkdB (B:)
vpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhl
avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrm
ehlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsv
iagaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyk
nskyhgvsllnppetlnl
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1pkdC (C:)
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1pkdD (D:)
vpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhl
avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrm
ehlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsv
iagaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyk
nskyhgvsllnppetlnl