PDB entry 1pjs

View 1pjs on RCSB PDB site
Description: The co-crystal structure of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis, in complex with it NAD cofactor
Class: transferase/oxidoreductase/lyase
Keywords: rossman fold, nucleotide binding motif, SAH, SAM, NAD, phosphoserine, TRANSFERASE/OXIDOREDUCTASE/LYASE COMPLEX
Deposited on 2003-06-03, released 2003-12-02
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.239
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Siroheme synthase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: CYSG OR STM3477
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25924 (0-456)
      • modified residue (127)
    Domains in SCOPe 2.01: d1pjsa1, d1pjsa2, d1pjsa3
  • Chain 'B':
    Compound: Siroheme synthase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: CYSG OR STM3477
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25924 (0-456)
      • modified residue (127)
    Domains in SCOPe 2.01: d1pjsb1, d1pjsb2, d1pjsb3
  • Heterogens: PO4, SAH, NAD, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pjsA (A:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavssggtspvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvrrdadrvfvgkragyhcvpqeeinqillreaqkgkrvvrlk
ggdpfifgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghl
ktggeldwenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvh
gvltqlgelaqqvespaliivgrvvalrdklnwfsnh

    Sequence, based on observed residues (ATOM records): (download) 
    >1pjsA (A:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavssggtspvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvrrdadrvfvvpqeeinqillreaqkgkrvvrlkggdpfifg
rggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtgeldwenlaae
kqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvhgvltqlgelaqqve
spaliivgrvvalrdklnwfsnh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pjsB (B:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavssggtspvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvrrdadrvfvgkragyhcvpqeeinqillreaqkgkrvvrlk
ggdpfifgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghl
ktggeldwenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvh
gvltqlgelaqqvespaliivgrvvalrdklnwfsnh

    Sequence, based on observed residues (ATOM records): (download) 
    >1pjsB (B:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavssggtspvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvrrdadrvfvgkragyhcvpqeeinqillreaqkgkrvvrlk
ggdpfifgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghg
geldwenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvhgvl
tqlgelaqqvespaliivgrvvalrdklnwfsnh