PDB entry 1pgf

View 1pgf on RCSB PDB site
Description: prostaglandin h2 synthase-1 complexed with 1-(4-iodobenzoyl)-5-methoxy-2-methylindole-3-acetic acid (iodoindomethacin), cis model
Class: oxidoreductase
Keywords: oxidoreductase, dioxygenase, peroxidase
Deposited on 1995-12-02, released 1997-01-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-09.
Experiment type: XRAY
Resolution: 4.5 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: prostaglandin h2 synthase-1
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • PIR A29947
    Domains in SCOPe 2.08: d1pgfa1, d1pgfa2
  • Chain 'B':
    Compound: prostaglandin h2 synthase-1
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • PIR A29947
    Domains in SCOPe 2.08: d1pgfb1, d1pgfb2
  • Heterogens: NAG, HEM, IMM

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1pgfA (A:)
    adpgapapvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrp
    spsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsn
    vsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqh
    fthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevypp
    sveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwg
    deqlfqtarliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnql
    yhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhi
    lhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefy
    pglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatl
    kklvclntktcpyvsfhvpdprqedrpgverpptel
    

    Sequence, based on observed residues (ATOM records): (download)
    >1pgfA (A:)
    vnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrpspsfihfl
    lthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsnvsyytril
    psvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqhfthqffkt
    sgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevyppsveeapvl
    mhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwgdeqlfqta
    rliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnqlyhwhplmp
    dsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhilhvavdvi
    kesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefypglllekc
    hpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatlkklvclnt
    ktcpyvsfhvp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1pgfB (B:)
    adpgapapvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrp
    spsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsn
    vsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqh
    fthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevypp
    sveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwg
    deqlfqtarliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnql
    yhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhi
    lhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefy
    pglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatl
    kklvclntktcpyvsfhvpdprqedrpgverpptel
    

    Sequence, based on observed residues (ATOM records): (download)
    >1pgfB (B:)
    vnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrpspsfihfl
    lthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsnvsyytril
    psvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqhfthqffkt
    sgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevyppsveeapvl
    mhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwgdeqlfqta
    rliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnqlyhwhplmp
    dsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhilhvavdvi
    kesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefypglllekc
    hpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatlkklvclnt
    ktcpyvsfhvp