PDB entry 1pd9

View 1pd9 on RCSB PDB site
Description: Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine antifolate Complex with Human Dihydrofolate Reductase
Class: oxidoreductase
Keywords: human dihydrofolate reductase inhibitor complexes
Deposited on 2003-05-19, released 2003-12-09
The last revision prior to the SCOP 1.75 freeze date was dated 2003-12-09, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.213
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: HOMO SAPIENS
    Gene: Dhfr
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1pd9a_
  • Heterogens: SO4, CO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1pd9A (A:)
    vgslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsi
    peknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssv
    ykeamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfe
    vyeknd