PDB entry 1p75

View 1p75 on RCSB PDB site
Description: Crystal structure of EHV4-TK complexed with TP5A
Class: transferase
Keywords: P-loop, Lid, TRANSFERASE
Deposited on 2003-04-30, released 2003-11-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.02 Å
R-factor: 0.211
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4 [TaxId:10331]
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (2-3)
    Domains in SCOPe 2.06: d1p75a1, d1p75a2
  • Chain 'B':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4 [TaxId:10331]
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (1-3)
    Domains in SCOPe 2.06: d1p75b1, d1p75b2
  • Chain 'C':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4 [TaxId:10331]
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (1-3)
    Domains in SCOPe 2.06: d1p75c1, d1p75c2
  • Chain 'D':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4 [TaxId:10331]
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (1-3)
    Domains in SCOPe 2.06: d1p75d1, d1p75d2
  • Heterogens: SO4, T5A, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1p75A (A:)
gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
vesllplmsstlsdfdsasaleraartfnaemgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1p75A (A:)
hmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiydt
qnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdrh
pvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrarge
qiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqervsp
elgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavves
llplmsstlsdfdsasaleraartfnaemgv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1p75B (B:)
gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
vesllplmsstlsdfdsasaleraartfnaemgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1p75B (B:)
shmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiyd
tqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdr
hpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrari
geqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqerv
spelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavv
esllplmsstlsdfdsasaleraartfnaemgv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1p75C (C:)
gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
vesllplmsstlsdfdsasaleraartfnaemgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1p75C (C:)
shmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiyd
tqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdr
hpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrgeq
iditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqervspe
lgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavvesl
lplmsstlsdfdsasaleraartfnaemgv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1p75D (D:)
gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
vesllplmsstlsdfdsasaleraartfnaemgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1p75D (D:)
shmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiyd
tqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdr
hpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrgeqid
itliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqervspelg
dtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavvesllp
lmsstlsdfdsasaleraartfnaemgv