PDB entry 1p73

View 1p73 on RCSB PDB site
Description: Crystal structure of EHV4-TK complexed with TP4A
Class: transferase
Keywords: P-loop, Lid
Deposited on 2003-04-30, released 2003-11-04
The last revision prior to the SCOP 1.75 freeze date was dated 2003-11-04, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.219
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (3)
    Domains in SCOP 1.75: d1p73a_
  • Chain 'B':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (3)
    Domains in SCOP 1.75: d1p73b_
  • Chain 'C':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (3)
    Domains in SCOP 1.75: d1p73c_
  • Chain 'D':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (2-3)
    Domains in SCOP 1.75: d1p73d_
  • Heterogens: SO4, 4TA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1p73A (A:)
gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
vesllplmsstlsdfdsasaleraartfnaemgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1p73A (A:)
mvtivriyldgvygigksttgrvmassptlyfpepmaywrtlfetdvisgiydtqnrkvd
daalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdrhpvastvcfpaar
yllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrarigeqiditliatlr
nvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqervspelgdtlfalfk
tqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavvesllplmsstlsd
fdsasaleraartfnaemgv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1p73B (B:)
gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
vesllplmsstlsdfdsasaleraartfnaemgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1p73B (B:)
mvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiydtq
nrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdrhp
vastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrarige
qiditliatlrnvyfmlvntchflrsgrvwrdgwgelptsaykhratqmdafqervspel
gdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavvesll
plmsstlsdfdsasaleraartfnaemgv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1p73C (C:)
gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
vesllplmsstlsdfdsasaleraartfnaemgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1p73C (C:)
mvtivriyldgvygigksttgrvmassptlyfpepmaywrtlfetdvisgiydtqnrvdd
aalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdrhpvastvcfpaary
llgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrareqiditliatlrnvy
fmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqervspelgdtlfalfktqe
llddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavvesllplmsstlsdfds
asaleraartfnaemgv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1p73D (D:)
gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
vesllplmsstlsdfdsasaleraartfnaemgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1p73D (D:)
hmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiydt
qnravddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdrhpvastv
cfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrarigeqidit
liatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqervspelgdt
lfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavvesllplm
sstlsdfdsasaleraartfnaemgv