PDB entry 1p6x

View 1p6x on RCSB PDB site
Description: Crystal structure of EHV4-TK complexed with Thy and SO4
Class: transferase
Keywords: P-loop, Lid, TRANSFERASE
Deposited on 2003-04-30, released 2003-11-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.192
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4 [TaxId:10331]
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-333)
      • cloning artifact (1-3)
    Domains in SCOPe 2.06: d1p6xa1, d1p6xa2
  • Chain 'B':
    Compound: Thymidine kinase
    Species: Equid herpesvirus 4 [TaxId:10331]
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24425 (4-End)
      • cloning artifact (2-3)
    Domains in SCOPe 2.06: d1p6xb1, d1p6xb2
  • Heterogens: SO4, THM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1p6xA (A:)
    gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
    dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
    rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
    igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
    vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
    vesllplmsstlsdfdsasaleraartfnaemgv
    

    Sequence, based on observed residues (ATOM records): (download)
    >1p6xA (A:)
    shmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiyd
    tqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdr
    hpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrari
    geqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqerv
    spelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavv
    esllplmsstlsdfdsasaleraartfnaemgv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1p6xB (B:)
    gshmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiy
    dtqnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfd
    rhpvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrar
    igeqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqer
    vspelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaav
    vesllplmsstlsdfdsasaleraartfnaemgv
    

    Sequence, based on observed residues (ATOM records): (download)
    >1p6xB (B:)
    hmvtivriyldgvygigksttgrvmasaasggsptlyfpepmaywrtlfetdvisgiydt
    qnrkqqgnlavddaalitahyqsrfttpylilhdhtctlfggnslqrgtqpdltlvfdrh
    pvastvcfpaaryllgdmsmcalmamvatlprepqggnivvttlnveehirrlrtrarig
    eqiditliatlrnvyfmlvntchflrsgrvwrdgwgelptscgaykhratqmdafqervs
    pelgdtlfalfktqellddrgvilevhawaldalmlklrnlnvfsadlsgtprqcaavve
    sllplmsstlsdfdsasaleraartfnaemg