PDB entry 1p62

View 1p62 on RCSB PDB site
Description: Structure of human dCK complexed with gemcitabine and ADP-MG
Class: transferase
Keywords: nucleoside kinase, P-loop, gemcitabine, TRANSFERASE
Deposited on 2003-04-28, released 2003-07-01
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.182
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Deoxycytidine kinase
    Species: Mus musculus [TaxId:10090]
    Gene: DCK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1p62b_
  • Heterogens: MG, ADP, GEO, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1p62B (B:)
    gshmatppkrscpsfsassegtrikkisiegniaagkstfvnilkqlcedwevvpepvar
    wcnvqstqdefeeltmsqknggnvlqmmyekperwsftfqtyaclsriraqlaslngklk
    daekpvlffersvysdryifasnlyesecmnetewtiyqdwhdwmnnqfgqsleldgiiy
    lqatpetclhriylrgrneeqgipleyleklhykheswllhrtlktnfdylqevpiltld
    vnedfkdkyeslvekvkeflstl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1p62B (B:)
    rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstnggnvlqmmyekper
    wsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesecmnete
    wtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhyk
    heswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl