PDB entry 1p49

View 1p49 on RCSB PDB site
Description: Structure of Human Placental Estrone/DHEA Sulfatase
Class: hydrolase
Keywords: steroid biosynthesis, steroid sulfatase, estrone sulfate, dehydroepiandrosterone sulfate, human placental enzyme, endoplasmic reticulum membrane-bound, HYDROLASE
Deposited on 2003-04-21, released 2003-08-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-12-02, with a file datestamp of 2015-11-27.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: steryl-sulfatase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08842
      • modified residue (53)
    Domains in SCOPe 2.07: d1p49a_
  • Heterogens: BOG, NAG, CA, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1p49A (A:)
haasrpniilvmaddlgigdpgcygnktirtpnidrlasggvkltqhlaasplatpsraa
fmtgrypvrsgmaswsrtgvflftassgglptdeitfakllkdqgystaligkwhlgmsc
hsktdfchhplhhgfnyfygisltnlrdckpgegsvfttgfkrlvflplqivgvtlltla
alnclgllhvplgvffsllflaaliltlflgflhyfrplncfmmrnyeiiqqpmsydnlt
qrltveaaqfiqrntetpfllvlsylhvhtalfsskdfagksqhgvygdaveemdwsvgq
ilnlldelrlandtliyftsdqgahveevsskgeihggsngiykggkannweggirvpgi
lrwprviqagqkideptsnmdifptvaklagaplpedriidgrdlmpllegksqrsdhef
lfhycnaylnavrwhpqnstsiwkaffftpnfnpvgsngcfathvcfcfgsyvthhdppl
lfdiskdprernpltpaseprfyeilkvmqeaadrhtqtlpevpdqfswnnflwkpwlql
ccpstglscqcdrekqdkrlsr

    Sequence, based on observed residues (ATOM records): (download) 
    >1p49A (A:)
aasrpniilvmaddlgigdpgcygnktirtpnidrlasggvkltqhlaasplatpsraaf
mtgrypvrsgmaswsrtgvflftassgglptdeitfakllkdqgystaligkwhlgmsch
sktdfchhplhhgfnyfygisltnlrdckpgegsvfttgfkrlvflplqivgvtlltlaa
lnclgllhvplgvffsllflaaliltlflgflhyfrplncfmmrnyeiiqqpmsydnltq
rltveaaqfiqrntetpfllvlsylhvhtalfsskdfagksqhgvygdaveemdwsvgqi
lnlldelrlandtliyftsdqgahveevsskgeihggsngiykggkannweggirvpgil
rwprviqagqkideptsnmdifptvaklagaplpedriidgrdlmpllegksqrsdhefl
fhycnaylnavrwhpqnstsiwkaffftpnfnpvcfathvcfcfgsyvthhdppllfdis
kdprernpltpaseprfyeilkvmqeaadrhtqtlpevpdqfswnnflwkpwlqlccpst
glscqcdre