PDB entry 1p0s

View 1p0s on RCSB PDB site
Description: Crystal Structure of Blood Coagulation Factor Xa in Complex with Ecotin M84R
Class: hydrolase
Keywords: factor xa, serine protease, ecotin M84R, serine protease inhibitor, HYDROLASE
Deposited on 2003-04-10, released 2003-08-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.207
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: Ecotin precursor
    Species: Escherichia coli [TaxId:562]
    Gene: ECO OR ETI OR B2209
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23827 (Start-141)
      • engineered (83)
    Domains in SCOPe 2.06: d1p0se_
  • Chain 'H':
    Compound: Coagulation factor X precursor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1p0sh_
  • Chain 'L':
    Compound: Coagulation factor X precursor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00742 (Start-137)
      • modified residue (5-6)
      • modified residue (13)
      • modified residue (15)
      • modified residue (18-19)
      • modified residue (24-25)
      • modified residue (28)
      • modified residue (31)
      • modified residue (38)
    Domains in SCOPe 2.06: d1p0sl1, d1p0sl2
  • Heterogens: MG, NA, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1p0sE (E:)
aesvqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggkle
nktlegwgydyyvfdkvsspvstrmacpdgkkekkfvtaylgdagmlrynsklpivvytp
dnvdvkyrvwkaeekidnavvr

    Sequence, based on observed residues (ATOM records): (download) 
    >1p0sE (E:)
vqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggklenkt
legwgydyyvfdkvsspvstrmacpdgkkekkfvtaylgdagmlrynsklpivvytpdnv
dvkyrvwkaeekidnavvr

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1p0sH (H:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
kshapevitssplk

    Sequence, based on observed residues (ATOM records): (download) 
    >1p0sH (H:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1p0sL (L:)
ansfleemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqcetspcqnqgk
ckdglgeytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcscargytladn
gkaciptgpypcgkqtle

    Sequence, based on observed residues (ATOM records): (download) 
    >1p0sL (L:)
sfleemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqklcsldngdcdqf
cheeqnsvvcscargytladngkaciptgpypcgkqtle