PDB entry 1p0s

View 1p0s on RCSB PDB site
Description: Crystal Structure of Blood Coagulation Factor Xa in Complex with Ecotin M84R
Class: hydrolase
Keywords: factor xa, serine protease, ecotin M84R, serine protease inhibitor
Deposited on 2003-04-10, released 2003-08-26
The last revision prior to the SCOP 1.73 freeze date was dated 2003-08-26, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.207
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: Ecotin precursor
    Species: Escherichia coli
    Gene: ECO OR ETI OR B2209
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23827 (Start-141)
      • engineered (83)
    Domains in SCOP 1.73: d1p0se_
  • Chain 'H':
    Compound: Coagulation factor X precursor
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1p0sh_
  • Chain 'L':
    Compound: Coagulation factor X precursor
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00742 (Start-137)
      • modified residue (5-6)
      • modified residue (13)
      • modified residue (15)
      • modified residue (18-19)
      • modified residue (24-25)
      • modified residue (28)
      • modified residue (31)
      • modified residue (38)
    Domains in SCOP 1.73: d1p0sl1, d1p0sl2
  • Heterogens: MG, NA, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1p0sE (E:)
    aesvqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggkle
    nktlegwgydyyvfdkvsspvstrmacpdgkkekkfvtaylgdagmlrynsklpivvytp
    dnvdvkyrvwkaeekidnavvr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1p0sE (E:)
    vqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggklenkt
    legwgydyyvfdkvsspvstrmacpdgkkekkfvtaylgdagmlrynsklpivvytpdnv
    dvkyrvwkaeekidnavvr
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1p0sH (H:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
    kshapevitssplk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1p0sH (H:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >1p0sL (L:)
    ansfleemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqcetspcqnqgk
    ckdglgeytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcscargytladn
    gkaciptgpypcgkqtle
    

    Sequence, based on observed residues (ATOM records): (download)
    >1p0sL (L:)
    sfleemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqklcsldngdcdqf
    cheeqnsvvcscargytladngkaciptgpypcgkqtle