PDB entry 1oyh

View 1oyh on RCSB PDB site
Description: Crystal Structure of P13 Alanine Variant of Antithrombin
Class: blood clotting
Keywords: thrombin; inhibition; heparin analogue; SERINE PROTEASE INHIBITOR, BLOOD CLOTTING
Deposited on 2003-04-04, released 2004-04-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01008
      • engineered (136)
      • engineered (380)
    Domains in SCOPe 2.07: d1oyhi_
  • Chain 'L':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1oyhl_
  • Heterogens: NAG, NDG, BMA, MAN, HOH

PDB Chain Sequences:

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >1oyhI (I:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegsaaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1oyhI (I:)
    vdictakprdipmnpmciyrspekipeatnrrvwelskansrfattfyqhladskndndn
    iflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkan
    kasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnkte
    gritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqe
    gkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemm
    lvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflev
    neegsaaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >1oyhL (L:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1oyhL (L:)
    vdictakprdipmnpmciyrspeatnrrvwelskansrfattfyqhladskndndnifls
    plsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkankssk
    lvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegrit
    dvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfr
    yrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvh
    mprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneeg
    seaaastavviagrslnprvtfkanrpflvfirevplntiifmgrvanpc