PDB entry 1ox5

View 1ox5 on RCSB PDB site
Description: towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase
Class: transferase, lyase
Keywords: complex cyclization; imidazole glycerophosphate synthase, transferase, lyase
Deposited on 2003-04-01, released 2003-06-17
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.223
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Imidazole glycerol phosphate synthase hisHF
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: HIS7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33734 (3-End)
      • cloning artifact (0-2)
      • modified residue (85)
      • cloning artifact (1-2)
    Domains in SCOPe 2.03: d1ox5a1, d1ox5a2
  • Chain 'B':
    Compound: Imidazole glycerol phosphate synthase hisHF
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: HIS7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33734
      • modified residue (85)
    Domains in SCOPe 2.03: d1ox5b1, d1ox5b2
  • Heterogens: NI, 1PR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ox5A (A:)
gshmpvvhvidvesgnlqsltnaiehlgyevqlvkspkdfnisgtsrlilpgvgnyghfv
dnlfnrgfekpireyiesgkpimgicvglqalfagsvespkstglnyidfklsrfddsek
pvpeigwnscipsenlffgldpykryyfvhsfaailnsekkknlendgwkiakakygsee
fiaavnknnifatqfhpeksgkaglnvienflkqqsppipnysaeekellmndysnyglt
rriiacldvrtndqgdlvvtkgdqydvreksdgkgvrnlgkpvqlaqkyyqqgadevtfl
nitsfrdcplkdtpmlevlkqaaktvfvpltvgggikdivdvdgtkipalevaslyfrsg
adkvsigtdavyaaekyyelgnrgdgtspietiskaygaqavvisvdpkrvyvnsqadtk
nkvfeteypgpngekycwyqctikggresrdlgvweltracealgageillncidkdgsn
sgydleliehvkdavkipviassgagvpehfeeaflktradaclgagmfhrgeftvndvk
eyllehglkvrmdee

    Sequence, based on observed residues (ATOM records): (download) 
    >1ox5A (A:)
gshmpvvhvidvesgnlqsltnaiehlgyevqlvkspkdfnisgtsrlilpgvgnyghfv
dnlfnrgfekpireyiesgkpimgicvglqalfagsvespkstglnyidfklsrfddsek
pvpeigwnscipsenlffgldpykryyfvhsfaailnsekkknlendgwkiakakygsee
fiaavnknnifatqfhpeksgkaglnvienflkqqsppipnysaeekellmndysnyglt
rriiacldvrtndqgdlvvtklgkpvqlaqkyyqqgadevtflnitcplkdtpmlevlkq
aaktvfvpltvgggikdivdvdgtkipalevaslyfrsgadkvsigtdavyaaekyyelg
nrgdgtspietiskaygaqavvisvdpkrvyvnsqadtknkvfeteypgpngekycwyqc
tikggresrdlgvweltracealgageillncidkdgsnsgydleliehvkdavkipvia
ssgagvpehfeeaflktradaclgagmfhrgeftvndvkeyllehglkvrmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ox5B (B:)
gshmpvvhvidvesgnlqsltnaiehlgyevqlvkspkdfnisgtsrlilpgvgnyghfv
dnlfnrgfekpireyiesgkpimgicvglqalfagsvespkstglnyidfklsrfddsek
pvpeigwnscipsenlffgldpykryyfvhsfaailnsekkknlendgwkiakakygsee
fiaavnknnifatqfhpeksgkaglnvienflkqqsppipnysaeekellmndysnyglt
rriiacldvrtndqgdlvvtkgdqydvreksdgkgvrnlgkpvqlaqkyyqqgadevtfl
nitsfrdcplkdtpmlevlkqaaktvfvpltvgggikdivdvdgtkipalevaslyfrsg
adkvsigtdavyaaekyyelgnrgdgtspietiskaygaqavvisvdpkrvyvnsqadtk
nkvfeteypgpngekycwyqctikggresrdlgvweltracealgageillncidkdgsn
sgydleliehvkdavkipviassgagvpehfeeaflktradaclgagmfhrgeftvndvk
eyllehglkvrmdee

    Sequence, based on observed residues (ATOM records): (download) 
    >1ox5B (B:)
vvhvidvesgnlqsltnaiehlgyevqlvkspkdfnisgtsrlilpgvgnyghfvdnlfn
rgfekpireyiesgkpimgicvglqalfagsvespkstglnyidfklsrfddsekpvpei
gwnscipsenlffgldpykryyfvhsfaailnsekkknlendgwkiakakygseefiaav
nknnifatqfhpeksgkaglnvienflkqqsppipnysaeekellmndysnygltrriia
cldvrtndqgdlvvtklgkpvqlaqkyyqqgadevtflnitcplkdtpmlevlkqaaktv
fvpltvgggikdivdvdgtkipalevaslyfrsgadkvsigtdavyaaekyyelgnrgdg
tspietiskaygaqavvisvdpkrvyvnsqadtknkvfeteypgpngekycwyqctikgg
resrdlgvweltracealgageillncidkdgsnsgydleliehvkdavkipviassgag
vpehfeeaflktradaclgagmfhrgeftvndvkeyllehglkvrmd