PDB entry 1ox4

View 1ox4 on RCSB PDB site
Description: towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase
Class: transferase, lyase
Keywords: complex cyclization; imidazole glycerophosphate synthase, transferase, lyase
Deposited on 2003-04-01, released 2003-06-17
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.228
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Imidazole glycerol phosphate synthase hisHF
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: HIS7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33734 (3-End)
      • cloning artifact (0-2)
    Domains in SCOPe 2.05: d1ox4a1, d1ox4a2
  • Chain 'B':
    Compound: Imidazole glycerol phosphate synthase hisHF
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: HIS7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33734 (3-End)
      • cloning artifact (0-2)
      • modified residue (85)
    Domains in SCOPe 2.05: d1ox4b1, d1ox4b2
  • Heterogens: SO4, NI, POP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ox4A (A:)
gshmpvvhvidvesgnlqsltnaiehlgyevqlvkspkdfnisgtsrlilpgvgnyghfv
dnlfnrgfekpireyiesgkpimgicvglqalfagsvespkstglnyidfklsrfddsek
pvpeigwnscipsenlffgldpykryyfvhsfaailnsekkknlendgwkiakakygsee
fiaavnknnifatqfhpeksgkaglnvienflkqqsppipnysaeekellmndysnyglt
rriiacldvrtndqgdlvvtkgdqydvreksdgkgvrnlgkpvqlaqkyyqqgadevtfl
nitsfrdcplkdtpmlevlkqaaktvfvpltvgggikdivdvdgtkipalevaslyfrsg
adkvsigtdavyaaekyyelgnrgdgtspietiskaygaqavvisvdpkrvyvnsqadtk
nkvfeteypgpngekycwyqctikggresrdlgvweltracealgageillncidkdgsn
sgydleliehvkdavkipviassgagvpehfeeaflktradaclgagmfhrgeftvndvk
eyllehglkvrmdee

    Sequence, based on observed residues (ATOM records): (download) 
    >1ox4A (A:)
gshmpvvhvidvesgnlqsltnaiehlgyevqlvkspkdfnisgtsrlilpgvgnyghfv
dnlfnrgfekpireyiesgkpimgicvglqalfagsvespkstglnyidfklsrfddsek
pvpeigwnscipsenlffgldpykryyfvhsfaailnsekkknlendgwkiakakygsee
fiaavnknnifatqfhpeksgkaglnvienflkqqsppipnysaeekellmndysnyglt
rriiacldvrtndqgdlvvtkgdlgkpvqlaqkyyqqgadevtflnitcplkdtpmlevl
kqaaktvfvpltvgggikdivdvdgtkipalevaslyfrsgadkvsigtdavyaaekyye
lgnrgdgtspietiskaygaqavvisvdpkrvyvnsqadtknkvfeteypgpngekycwy
qctikggresrdlgvweltracealgageillncidkdgsnsgydleliehvkdavkipv
iassgagvpehfeeaflktradaclgagmfhrgeftvndvkeyllehglkvrmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ox4B (B:)
gshmpvvhvidvesgnlqsltnaiehlgyevqlvkspkdfnisgtsrlilpgvgnyghfv
dnlfnrgfekpireyiesgkpimgicvglqalfagsvespkstglnyidfklsrfddsek
pvpeigwnscipsenlffgldpykryyfvhsfaailnsekkknlendgwkiakakygsee
fiaavnknnifatqfhpeksgkaglnvienflkqqsppipnysaeekellmndysnyglt
rriiacldvrtndqgdlvvtkgdqydvreksdgkgvrnlgkpvqlaqkyyqqgadevtfl
nitsfrdcplkdtpmlevlkqaaktvfvpltvgggikdivdvdgtkipalevaslyfrsg
adkvsigtdavyaaekyyelgnrgdgtspietiskaygaqavvisvdpkrvyvnsqadtk
nkvfeteypgpngekycwyqctikggresrdlgvweltracealgageillncidkdgsn
sgydleliehvkdavkipviassgagvpehfeeaflktradaclgagmfhrgeftvndvk
eyllehglkvrmdee

    Sequence, based on observed residues (ATOM records): (download) 
    >1ox4B (B:)
gshmpvvhvidvesgnlqsltnaiehlgyevqlvkspkdfnisgtsrlilpgvgnyghfv
dnlfnrgfekpireyiesgkpimgicvglqalfagsvespkstglnyidfklsrfddsek
pvpeigwnscipsenlffgldpykryyfvhsfaailnsekkknlendgwkiakakygsee
fiaavnknnifatqfhpeksgkaglnvienflkqqsppipnysaeekellmndysnyglt
rriiacldvrtndqgdlvvtkgdlgkpvqlaqkyyqqgadevtflnitsfrdcplkdtpm
levlkqaaktvfvpltvgggikdivdvdgtkipalevaslyfrsgadkvsigtdavyaae
kyyelgnrgdgtspietiskaygaqavvisvdpkrvyvnsqadtknkvfeteypgpngek
ycwyqctikggresrdlgvweltracealgageillncidkdgsnsgydleliehvkdav
kipviassgagvpehfeeaflktradaclgagmfhrgeftvndvkeyllehglkvrmd