PDB entry 1ow8

View 1ow8 on RCSB PDB site
Description: Paxillin LD2 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
Class: transferase
Keywords: 4 helical bundle, amphiphatic helix
Deposited on 2003-03-28, released 2003-10-21
The last revision prior to the SCOP 1.73 freeze date was dated 2003-10-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.237
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Focal adhesion kinase 1
    Species: HOMO SAPIENS
    Gene: PTK2 OR FAK1 OR FAK
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ow8a_
  • Chain 'B':
    Compound: Focal adhesion kinase 1
    Species: HOMO SAPIENS
    Gene: PTK2 OR FAK1 OR FAK
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ow8b_
  • Chain 'C':
    Compound: Focal adhesion kinase 1
    Species: HOMO SAPIENS
    Gene: PTK2 OR FAK1 OR FAK
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ow8c_
  • Chain 'D':
    Compound: Paxillin
    Species: synthetic, synthetic
  • Chain 'F':
    Compound: Paxillin
    Species: synthetic, synthetic
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ow8A (A:)
sspadsynegvklqpqeisppptanldrsndkvyenvtglvkaviemsskiqpappeeyv
pmvkevglalrtllatvdetipllpasthreiemaqkllnsdlgelinkmklaqqyvmts
lqqeykkqmltaahalavdaknlldvidqarlkmlgqtrph

    Sequence, based on observed residues (ATOM records): (download) 
    >1ow8A (A:)
nldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrtllatvdetipll
pasthreiemaqkllnsdlgelinkmklaqqyvmtslqqeykkqmltaahalavdaknll
dvidqarlkmlgqt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ow8B (B:)
sspadsynegvklqpqeisppptanldrsndkvyenvtglvkaviemsskiqpappeeyv
pmvkevglalrtllatvdetipllpasthreiemaqkllnsdlgelinkmklaqqyvmts
lqqeykkqmltaahalavdaknlldvidqarlkmlgqtrph

    Sequence, based on observed residues (ATOM records): (download) 
    >1ow8B (B:)
qeisppptanldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrtlla
tvdetipllpasthreiemaqkllnsdlgelinkmklaqqyvmtslqqeykkqmltaaha
lavdaknlldvidqarlkmlg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ow8C (C:)
sspadsynegvklqpqeisppptanldrsndkvyenvtglvkaviemsskiqpappeeyv
pmvkevglalrtllatvdetipllpasthreiemaqkllnsdlgelinkmklaqqyvmts
lqqeykkqmltaahalavdaknlldvidqarlkmlgqtrph

    Sequence, based on observed residues (ATOM records): (download) 
    >1ow8C (C:)
pqeisppptanldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrtll
atvdetipllpasthreiemaqkllnsdlgelinkmklaqqyvmtslqqeykkqmltaah
alavdaknlldvidqarlkmlg

  • Chain 'D':
    No sequence available.

  • Chain 'F':
    No sequence available.