PDB entry 1ow3

View 1ow3 on RCSB PDB site
Description: Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP
Class: gene regulation/signaling protein
Keywords: Complex, GTPase, GAP, transition state, GENE REGULATION-SIGNALING PROTEIN COMPLEX
Deposited on 2003-03-28, released 2003-05-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-04-16, with a file datestamp of 2014-04-11.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.188
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Rho-GTPase-activating protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RHOGAP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1ow3a_
  • Chain 'B':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RhoA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586
      • engineered (24)
    Domains in SCOPe 2.06: d1ow3b_
  • Heterogens: MG, GDP, MGF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ow3A (A:)
hvkleqlgiprqvlkyddflkstqkspatapkpmpprpplpnqqfgvslqhlqeknpeqe
pipivlretvaylqahalttegifrrsantqvvrevqqkynmglpvdfdqynelhlpavi
lktflrelpeplltfdlyphvvgflnidesqrvpatlqvlqtlpeenyqvlrfltaflvq
isahsdqnkmtntnlavvfgpnllwakdaaitlkainpintftkflldhqgelfpspdps
gl

    Sequence, based on observed residues (ATOM records): (download) 
    >1ow3A (A:)
plpnqqfgvslqhlqeknpeqepipivlretvaylqahalttegifrrsantqvvrevqq
kynmglpvdfdqynelhlpavilktflrelpeplltfdlyphvvgflnidesqrvpatlq
vlqtlpeenyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlkainp
intftkflldhqgelf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ow3B (B:)
maairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdt
agqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkd
lrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
arrgkkksgclvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1ow3B (B:)
airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalqa