PDB entry 1oit

View 1oit on RCSB PDB site
Description: imidazopyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation
Class: kinase
Keywords: protein kinase
Deposited on 2003-06-24, released 2003-09-04
The last revision prior to the SCOP 1.73 freeze date was dated 2003-09-11, with a file datestamp of 2007-07-06.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.22661
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24941 (Start-297)
      • conflict (115)
    Domains in SCOP 1.73: d1oita_
  • Heterogens: HDT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1oitA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglsfchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >1oitA (A:)
nfqkvekigegtygvvykarnklgevvalkkitaireisllkelnhpnivklldvihten
klylvfeflhqdlkkfmdasaltgiplpliksylfqllqglsfchshrvlhrdlkpqnll
integaikladfglaravvtlwyrapeillgckyystavdiwslgcifaemvtrralfpg
dseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsq
mlhydpnkrisakaalahpffqdvtkpvphlrl