PDB entry 1ohy

View 1ohy on RCSB PDB site
Description: 4-aminobutyrate-aminotransferase inactivated by gamma-ethynyl gaba
Class: transferase
Keywords: transferase, plp-dependent enzyme, aminotransferase, 4-aminobutyric acid, antiepileptic drug target, vigabatrin pyridoxal phosphate, neurotransmitter degradation, mitochondrion, transit peptide
Deposited on 2003-06-03, released 2003-10-16
The last revision prior to the SCOP 1.75 freeze date was dated 2004-01-02, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.198
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-aminobutyrate aminotransferase
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ohya_
  • Chain 'B':
    Compound: 4-aminobutyrate aminotransferase
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ohyb_
  • Chain 'C':
    Compound: 4-aminobutyrate aminotransferase
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ohyc_
  • Chain 'D':
    Compound: 4-aminobutyrate aminotransferase
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ohyd_
  • Heterogens: FE, PLP, S, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ohyA (A:)
sqaaakvdvefdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdv
dgnrmldlysqissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresll
svapkgmsqlitmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdy
silsfmgafhgrtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeear
cleevedlivkyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdev
qtgggstgkfwahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsk
nlllaeviniikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdes
irnklisiarnkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ohyA (A:)
fdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdvdgnrmldlys
qissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresllsvapkgmsql
itmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdysilsfmgafh
grtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeearcleevedliv
kyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdevqtgggstgkf
wahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsknlllaevini
ikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdesirnklisiar
nkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ohyB (B:)
sqaaakvdvefdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdv
dgnrmldlysqissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresll
svapkgmsqlitmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdy
silsfmgafhgrtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeear
cleevedlivkyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdev
qtgggstgkfwahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsk
nlllaeviniikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdes
irnklisiarnkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ohyB (B:)
fdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdvdgnrmldlys
qissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresllsvapkgmsql
itmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdysilsfmgafh
grtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeearcleevedliv
kyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdevqtgggstgkf
wahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsknlllaevini
ikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdesirnklisiar
nkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ohyC (C:)
sqaaakvdvefdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdv
dgnrmldlysqissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresll
svapkgmsqlitmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdy
silsfmgafhgrtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeear
cleevedlivkyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdev
qtgggstgkfwahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsk
nlllaeviniikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdes
irnklisiarnkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ohyC (C:)
fdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdvdgnrmldlys
qissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresllsvapkgmsql
itmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdysilsfmgafh
grtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeearcleevedliv
kyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdevqtgggstgkf
wahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsknlllaevini
ikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdesirnklisiar
nkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ohyD (D:)
sqaaakvdvefdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdv
dgnrmldlysqissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresll
svapkgmsqlitmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdy
silsfmgafhgrtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeear
cleevedlivkyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdev
qtgggstgkfwahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsk
nlllaeviniikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdes
irnklisiarnkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ohyD (D:)
fdydgplmktevpgprsrelmkqlniiqnaeavhffcnyeesrgnylvdvdgnrmldlys
qissipigyshpalvklvqqpqnvstfinrpalgilppenfveklresllsvapkgmsql
itmacgscsnenafktifmwyrskergqsafskeeletcminqapgcpdysilsfmgafh
grtmgclatthskaihkidipsfdwpiapfprlkypleefvkenqqeearcleevedliv
kyrkkkktvagiivepiqseggdnhasddffrklrdisrkhgcaflvdevqtgggstgkf
wahehwglddpadvmtfskkmmtggffhkeefrpnapyrifntwlgdpsknlllaevini
ikredllsnaahagkvlltglldlqarypqfisrvrgrgtfcsfdtpdesirnklisiar
nkgvmlggcgdksirfrptlvfrdhhahlflnifsdiladf