PDB entry 1ohs

View 1ohs on RCSB PDB site
Description: crystal structure of 5-3-ketosteroid isomerase mutant y14f/ d38n from pseudomonas testosteroni complexed with androstanedione
Class: isomerase
Keywords: isomerase, inhibitor, androstanedione
Deposited on 2003-05-30, released 2005-03-31
The last revision prior to the SCOP 1.73 freeze date was dated 2005-03-31, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.219
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: steroid delta-isomerase
  Species: Comamonas testosteroni
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00947
    • engineered mutation (13)
    • engineered mutation (37)
    • conflict (82)
  Domains in SCOP 1.73: d1ohsa1
• Chain 'B':
  Compound: steroid delta-isomerase
  Species: Comamonas testosteroni
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00947 (0-124)
    • engineered mutation (13)
    • engineered mutation (37)
    • conflict (82)
  Domains in SCOP 1.73: d1ohsb1
• Chain 'C':
  Compound: steroid delta-isomerase
  Species: Comamonas testosteroni
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00947
    • engineered mutation (13)
    • engineered mutation (37)
    • conflict (82)
  Domains in SCOP 1.73: d1ohsc1
• Chain 'D':
  Compound: steroid delta-isomerase
  Species: Comamonas testosteroni
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00947 (0-124)
    • engineered mutation (13)
    • engineered mutation (37)
    • conflict (82)
  Domains in SCOP 1.73: d1ohsd1
• Heterogens: 5SD, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ohsA (A:)
  mntpehmtavvqrfvaalnagdldgivalfaddatvenpvgseprsgtaairefyanslk
  lplaveltqevravaneaafafivsfeyqgrktvvapidhfrfngagkvvsmralfgekn
  ihaga
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ohsB (B:)
  mntpehmtavvqrfvaalnagdldgivalfaddatvenpvgseprsgtaairefyanslk
  lplaveltqevravaneaafafivsfeyqgrktvvapidhfrfngagkvvsmralfgekn
  ihaga
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ohsC (C:)
  mntpehmtavvqrfvaalnagdldgivalfaddatvenpvgseprsgtaairefyanslk
  lplaveltqevravaneaafafivsfeyqgrktvvapidhfrfngagkvvsmralfgekn
  ihaga
  

  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ohsD (D:)
  mntpehmtavvqrfvaalnagdldgivalfaddatvenpvgseprsgtaairefyanslk
  lplaveltqevravaneaafafivsfeyqgrktvvapidhfrfngagkvvsmralfgekn
  ihaga