PDB entry 1ogs

View 1ogs on RCSB PDB site
Description: human acid-beta-glucosidase
Class: hydrolase
Keywords: GAUCHER DISEASE, GLUCOSIDASE, GLUCOCEREBROSIDASE, CEREZYME HYDROLASE, GLYCOSIDASE, SPHINGOLIPID METABOLISM, GLYCOPROTE LYSOSOME, MEMBRANE, GAUCHER DISEASE, SIGNAL, DISEASE MUTATI POLYMORPHISM, ALTERNATIVE INITIATION, PHARMACEUTICAL, Israel Structural Proteomics Center, ISPC, Structural Genomics
Deposited on 2003-05-13, released 2003-07-03
The last revision prior to the SCOP 1.73 freeze date was dated 2003-10-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.195
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucosylceramidase
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ogsa1, d1ogsa2
  • Chain 'B':
    Compound: glucosylceramidase
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ogsb1, d1ogsb2
  • Heterogens: NDG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ogsA (A:)
arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanh
tgtgllltlqpeqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniir
vpmascdfsirtytyadtpddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwt
sptwlktngavngkgslkgqpgdiyhqtwaryfvkfldayaehklqfwavtaenepsagl
lsgypfqclgftpehqrdfiardlgptlansthhnvrllmlddqrlllphwakvvltdpe
aakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgskfweqsvrlgswdrg
mqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykqpmfyhl
ghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfl
etispgysihtylwhrq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ogsB (B:)
arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanh
tgtgllltlqpeqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniir
vpmascdfsirtytyadtpddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwt
sptwlktngavngkgslkgqpgdiyhqtwaryfvkfldayaehklqfwavtaenepsagl
lsgypfqclgftpehqrdfiardlgptlansthhnvrllmlddqrlllphwakvvltdpe
aakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgskfweqsvrlgswdrg
mqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykqpmfyhl
ghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfl
etispgysihtylwhrq