PDB entry 1og2

View 1og2 on RCSB PDB site
Description: structure of human cytochrome p450 cyp2c9
Class: electron transport
Keywords: drug metabolism, electron transport, oxidoreductase, heme, monooxygenase
Deposited on 2003-04-23, released 2003-07-17
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-11-09, with a file datestamp of 2011-11-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.21
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2C9
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1OG2 (471-End)
      • engineered mutation (186)
      • engineered mutation (195-196)
      • engineered mutation (200-203)
    • Uniprot P11712 (10-470)
    Domains in SCOPe 2.01: d1og2a_
  • Chain 'B':
    Compound: Cytochrome P450 2C9
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1OG2 (471-End)
      • engineered mutation (186)
      • engineered mutation (195-196)
      • engineered mutation (200-203)
    • Uniprot P11712 (10-470)
    Domains in SCOPe 2.01: d1og2b_
  • Heterogens: HEC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1og2A (A:)
makktsskgrppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvlhg
yeavkealidlgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkr
siedrvqeearclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlme
klnenieilsspwiqvynnfpalldyfpgthnkllknvafmksyilekvkehqesmdmnn
pqdfidcflmkmekekhnqpseftieslentavdlfgagtettsttlryalllllkhpev
takvqeeiervigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfrny
lipkgttilisltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgea
lagmelflfltsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipvhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1og2A (A:)
ppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvlhgyeavkealid
lgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkrsiedrvqeea
rclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlmeklnenieils
spwiqvynnfpalldyfpgthnkllknvafmksyilekvkehqesmdmnnpqdfidcflm
kmekekhnqpseftieslentavdlfgagtettsttlryalllllkhpevtakvqeeier
vigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfrnylipkgttili
sltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgealagmelflfl
tsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipvh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1og2B (B:)
makktsskgrppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvlhg
yeavkealidlgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkr
siedrvqeearclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlme
klnenieilsspwiqvynnfpalldyfpgthnkllknvafmksyilekvkehqesmdmnn
pqdfidcflmkmekekhnqpseftieslentavdlfgagtettsttlryalllllkhpev
takvqeeiervigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfrny
lipkgttilisltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgea
lagmelflfltsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipvhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1og2B (B:)
ppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvlhgyeavkealid
lgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkrsiedrvqeea
rclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlmeklnenieils
spwiqvynnfpalldyfpgthnkllknvafmksyilekvkehqesmdmnnpqdfidcflm
kmekekhnqpseftieslentavdlfgagtettsttlryalllllkhpevtakvqeeier
vigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfrnylipkgttili
sltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgealagmelflfl
tsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipvh