PDB entry 1ofq

View 1ofq on RCSB PDB site
Description: crystal structure of the tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from saccharomyces cerevisiae in complex with manganese(II)
Class: lyase
Keywords: beta-alpha-barrel, lyase, aromatic amino-acid biosynthesis synthase, aldolase, synthetase, manganese
Deposited on 2003-04-17, released 2004-04-15
The last revision prior to the SCOP 1.73 freeze date was dated 2005-05-26, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.221
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ofqa_
  • Chain 'B':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ofqb_
  • Chain 'C':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ofqc_
  • Chain 'D':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ofqd_
  • Heterogens: MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ofqA (A:)
msespmfaangmpkvnqgaeedvrilgydplaspallqvqipatptsletakrgrreaid
iitgkddrvlvivgpcsihdleaaqeyalrlkklsdelkgdlsiimraylekprttvgwk
glindpdvnntfninkglqsarqlfvnltniglpigsemldtispqyladlvsfgaigar
ttesqlhrelasglsfpvgfkngtdgtlnvavdacqaaahshhfmgvtkhgvaaitttkg
nehcfvilrggkkgtnydaksvaeakaqlpagsnglmidyshgnsnkdfrnqpkvndvvc
eqiangenaitgvmiesninegnqgipaegkaglkygvsitdacigwettedvlrklaaa
vrqrrevnkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ofqA (A:)
vrilgydplaspallqvqipatptsletakrgrreaidiitgkddrvlvivgpcsihdle
aaqeyalrlkklsdelkgdlsiimraylekpvgwkglindpdvnntfninkglqsarqlf
vnltniglpigsemldtispqyladlvsfgaigarttesqlhrelasglsfpvgfkngtd
gtlnvavdacqaaahshhfmgvthgvaaitttkgnehcfvilrggkkgtnydaksvaeak
aqlpagsnglmidyshgnsnkdfrnqpkvndvvceqiangenaitgvmiesninegnqgi
paegkaglkygvsitdacigwettedvlrklaaavrqrrevnk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ofqB (B:)
msespmfaangmpkvnqgaeedvrilgydplaspallqvqipatptsletakrgrreaid
iitgkddrvlvivgpcsihdleaaqeyalrlkklsdelkgdlsiimraylekprttvgwk
glindpdvnntfninkglqsarqlfvnltniglpigsemldtispqyladlvsfgaigar
ttesqlhrelasglsfpvgfkngtdgtlnvavdacqaaahshhfmgvtkhgvaaitttkg
nehcfvilrggkkgtnydaksvaeakaqlpagsnglmidyshgnsnkdfrnqpkvndvvc
eqiangenaitgvmiesninegnqgipaegkaglkygvsitdacigwettedvlrklaaa
vrqrrevnkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ofqB (B:)
vrilgydplaspallqvqipatptsletakrgrreaidiitgkddrvlvivgpcsihdle
aaqeyalrlkklsdelkgdlsiimrayleprttwkglindpdvnntfninkglqsarqlf
vnltniglpigsemldtispqyladlvsfgaigarttesqlhrelasglsfpvgfkngtd
gtlnvavdacqaaahshhfmgvtkhgvaaitttkgnehcfvilrggkkgtnydaksvaea
kaqlpagsnglmidyshgnsnkdfrnqpkvndvvceqiangenaitgvmiesninegnqg
iegkaglkygvsitdacigwettedvlrklaaavrqrrevnkk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ofqC (C:)
msespmfaangmpkvnqgaeedvrilgydplaspallqvqipatptsletakrgrreaid
iitgkddrvlvivgpcsihdleaaqeyalrlkklsdelkgdlsiimraylekprttvgwk
glindpdvnntfninkglqsarqlfvnltniglpigsemldtispqyladlvsfgaigar
ttesqlhrelasglsfpvgfkngtdgtlnvavdacqaaahshhfmgvtkhgvaaitttkg
nehcfvilrggkkgtnydaksvaeakaqlpagsnglmidyshgnsnkdfrnqpkvndvvc
eqiangenaitgvmiesninegnqgipaegkaglkygvsitdacigwettedvlrklaaa
vrqrrevnkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ofqC (C:)
vrilgydplaspallqvqipatptsletakrgrreaidiitgkddrvlvivgpcsihdle
aaqeyalrlkklsdelkgdlsiimraylekprvgwkglindpdvnntfninkglqsarql
fvnltniglpigsemldtispqyladlvsfgaigarttesqlhrelasglsfpvgfkngt
dgtlnvavdacqaaahshhfmgvthgvaaitttkgnehcfvilrggkkgtnydaksvaea
kaqlpagsnglmidyshgnsnkdfrnqpkvndvvceqiangenaitgvmiesninegnqg
ipaegkaglkygvsitdacigwettedvlrklaaavrqrrevnk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ofqD (D:)
msespmfaangmpkvnqgaeedvrilgydplaspallqvqipatptsletakrgrreaid
iitgkddrvlvivgpcsihdleaaqeyalrlkklsdelkgdlsiimraylekprttvgwk
glindpdvnntfninkglqsarqlfvnltniglpigsemldtispqyladlvsfgaigar
ttesqlhrelasglsfpvgfkngtdgtlnvavdacqaaahshhfmgvtkhgvaaitttkg
nehcfvilrggkkgtnydaksvaeakaqlpagsnglmidyshgnsnkdfrnqpkvndvvc
eqiangenaitgvmiesninegnqgipaegkaglkygvsitdacigwettedvlrklaaa
vrqrrevnkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ofqD (D:)
vrilgydplaspallqvqipatptsletakrgrreaidiitgkddrvlvivgpcsihdle
aaqeyalrlkklsdelkgdlsiimrayleprttvgwkglindpdvnntfninkglqsarq
lfvnltniglpigsemldtispqyladlvsfgaigarttesqlhrelasglsfpvgfkng
tdgtlnvavdacqaaahshhfmgvtkhgvaaitttkgnehcfvilrggkkgtnydaksva
eakaqlpagsnglmidyshgnsnkdfrnqpkvndvvceqiangenaitgvmiesninegn
qgipaegkaglkygvsitdacigwettedvlrklaaavrqrrevnk