PDB entry 1o9k

View 1o9k on RCSB PDB site
Description: crystal structure of the retinoblastoma tumour suppressor protein bound to e2f peptide
Class: apoptosis
Keywords: apoptosis, tumour suppressor, cell cycle regulation, DNA-binding
Deposited on 2002-12-16, released 2003-03-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.232
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoblastoma-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1o9ka_
  • Chain 'B':
    Compound: Retinoblastoma-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1o9kb_
  • Chain 'C':
    Compound: Retinoblastoma-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1o9kc_
  • Chain 'D':
    Compound: Retinoblastoma-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1o9kd_
  • Chain 'E':
    Compound: Retinoblastoma-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1o9ke_
  • Chain 'F':
    Compound: Retinoblastoma-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1o9kf_
  • Chain 'G':
    Compound: Retinoblastoma-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1o9kg_
  • Chain 'H':
    Compound: Retinoblastoma-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1o9kh_
  • Chain 'P':
    Compound: Transcription factor E2F1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: Transcription factor E2F1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: Transcription factor E2F1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: Transcription factor E2F1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1o9kA (A:)
htpvrtvmntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfa
kavgqgcveigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacal
evvmatysrstsqnldsgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhle
rcehrimeslawlsdsplfdlikqskdregptdhlesa

    Sequence, based on observed residues (ATOM records): (download) 
    >1o9kA (A:)
mntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfakavgqgc
veigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacalevvmaty
srssgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhlercehrimeslawl
sdsplfdlikqskd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1o9kB (B:)
fqtqkplkstslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelm
rdrhldqimmcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivf
ynsvfmqrlktnilqyastrpptlspiphipr

    Sequence, based on observed residues (ATOM records): (download) 
    >1o9kB (B:)
stslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelmrdrhldqi
mmcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivfynsvfmqr
lktnilqyastrpptlspiphipr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1o9kC (C:)
htpvrtvmntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfa
kavgqgcveigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacal
evvmatysrstsqnldsgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhle
rcehrimeslawlsdsplfdlikqskdregptdhlesa

    Sequence, based on observed residues (ATOM records): (download) 
    >1o9kC (C:)
mntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfakavgqgc
veigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacalevvmaty
srssgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhlercehrimeslawl
sdsplfdlikqskd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1o9kD (D:)
fqtqkplkstslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelm
rdrhldqimmcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivf
ynsvfmqrlktnilqyastrpptlspiphipr

    Sequence, based on observed residues (ATOM records): (download) 
    >1o9kD (D:)
stslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelmrdrhldqi
mmcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivfynsvfmqr
lktnilqyastrpptlspiphipr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1o9kE (E:)
htpvrtvmntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfa
kavgqgcveigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacal
evvmatysrstsqnldsgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhle
rcehrimeslawlsdsplfdlikqskdregptdhlesa

    Sequence, based on observed residues (ATOM records): (download) 
    >1o9kE (E:)
mntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfakavgqgc
veigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacalevvmaty
srssgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhlercehrimeslawl
sdsplfdlikqskd

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1o9kF (F:)
fqtqkplkstslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelm
rdrhldqimmcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivf
ynsvfmqrlktnilqyastrpptlspiphipr

    Sequence, based on observed residues (ATOM records): (download) 
    >1o9kF (F:)
stslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelmrdrhldqi
mmcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivfynsvfmqr
lktnilqyastrpptlspiphipr

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1o9kG (G:)
htpvrtvmntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfa
kavgqgcveigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacal
evvmatysrstsqnldsgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhle
rcehrimeslawlsdsplfdlikqskdregptdhlesa

    Sequence, based on observed residues (ATOM records): (download) 
    >1o9kG (G:)
mntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfakavgqgc
veigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacalevvmaty
srssgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhlercehrimeslawl
sdsplfdlikqskd

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1o9kH (H:)
fqtqkplkstslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelm
rdrhldqimmcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivf
ynsvfmqrlktnilqyastrpptlspiphipr

    Sequence, based on observed residues (ATOM records): (download) 
    >1o9kH (H:)
stslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelmrdrhldqi
mmcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivfynsvfmqr
lktnilqyastrpptlspiphipr

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'R':
    No sequence available.

  • Chain 'S':
    No sequence available.