PDB entry 1o66

View 1o66 on RCSB PDB site
Description: Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase
Class: transferase
Keywords: structural genomics, transferase
Deposited on 2003-10-23, released 2003-11-11
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.231
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-methyl-2-oxobutanoate hydroxymethyltransferase
    Species: NEISSERIA MENINGITIDIS [TaxId:491]
    Gene: PANB, NMB0870
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZW6 (3-End)
      • cloning artifact (2)
      • modified residue (11)
      • modified residue (20)
      • modified residue (32)
      • modified residue (39)
      • modified residue (48)
      • modified residue (64)
      • modified residue (79)
      • modified residue (104)
      • modified residue (110)
      • modified residue (119)
      • modified residue (128)
      • modified residue (179)
      • modified residue (214)
      • modified residue (217)
      • modified residue (233)
    Domains in SCOPe 2.06: d1o66a1, d1o66a2
  • Chain 'B':
    Compound: 3-methyl-2-oxobutanoate hydroxymethyltransferase
    Species: NEISSERIA MENINGITIDIS [TaxId:491]
    Gene: PANB, NMB0870
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZW6 (3-End)
      • cloning artifact (1-2)
      • modified residue (11)
      • modified residue (20)
      • modified residue (32)
      • modified residue (39)
      • modified residue (48)
      • modified residue (64)
      • modified residue (79)
      • modified residue (104)
      • modified residue (110)
      • modified residue (119)
      • modified residue (128)
      • modified residue (179)
      • modified residue (214)
      • modified residue (217)
      • modified residue (233)
    Domains in SCOPe 2.06: d1o66b1, d1o66b2
  • Chain 'C':
    Compound: 3-methyl-2-oxobutanoate hydroxymethyltransferase
    Species: NEISSERIA MENINGITIDIS [TaxId:491]
    Gene: PANB, NMB0870
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZW6 (3-End)
      • cloning artifact (1-2)
      • modified residue (11)
      • modified residue (20)
      • modified residue (32)
      • modified residue (39)
      • modified residue (48)
      • modified residue (64)
      • modified residue (79)
      • modified residue (104)
      • modified residue (110)
      • modified residue (119)
      • modified residue (128)
      • modified residue (179)
      • modified residue (214)
      • modified residue (217)
      • modified residue (233)
    Domains in SCOPe 2.06: d1o66c1, d1o66c2
  • Chain 'D':
    Compound: 3-methyl-2-oxobutanoate hydroxymethyltransferase
    Species: NEISSERIA MENINGITIDIS [TaxId:491]
    Gene: PANB, NMB0870
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZW6 (3-End)
      • cloning artifact (2)
      • modified residue (11)
      • modified residue (20)
      • modified residue (32)
      • modified residue (39)
      • modified residue (48)
      • modified residue (64)
      • modified residue (79)
      • modified residue (104)
      • modified residue (110)
      • modified residue (119)
      • modified residue (128)
      • modified residue (179)
      • modified residue (214)
      • modified residue (217)
      • modified residue (233)
    Domains in SCOPe 2.06: d1o66d1, d1o66d2
  • Chain 'E':
    Compound: 3-methyl-2-oxobutanoate hydroxymethyltransferase
    Species: NEISSERIA MENINGITIDIS [TaxId:491]
    Gene: PANB, NMB0870
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JZW6 (3-End)
      • cloning artifact (1-2)
      • modified residue (11)
      • modified residue (20)
      • modified residue (32)
      • modified residue (39)
      • modified residue (48)
      • modified residue (64)
      • modified residue (79)
      • modified residue (104)
      • modified residue (110)
      • modified residue (119)
      • modified residue (128)
      • modified residue (179)
      • modified residue (214)
      • modified residue (217)
      • modified residue (233)
    Domains in SCOPe 2.06: d1o66e1, d1o66e2
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1o66A (A:)
mslitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpv
slrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwm
aetteflqmrgipvcahigltpqsvfafggykvqgrggkaqallndakahddagaavvlm
ecvlaelakkvtetvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsv
qaavrayvaevkaktfpaaehifadeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1o66A (A:)
litvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpvsl
rdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwmae
tteflqmrgipvcahigltpqsvfakaqallndakahddagaavvlmecvlaelakkvte
tvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsvqaavrayvaevka
ktfpaaehi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1o66B (B:)
mslitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpv
slrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwm
aetteflqmrgipvcahigltpqsvfafggykvqgrggkaqallndakahddagaavvlm
ecvlaelakkvtetvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsv
qaavrayvaevkaktfpaaehifadeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1o66B (B:)
slitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpvs
lrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwma
etteflqmrgipvcahigltpqsvfaggkaqallndakahddagaavvlmecvlaelakk
vtetvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsvqaavrayvae
vkaktfpa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1o66C (C:)
mslitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpv
slrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwm
aetteflqmrgipvcahigltpqsvfafggykvqgrggkaqallndakahddagaavvlm
ecvlaelakkvtetvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsv
qaavrayvaevkaktfpaaehifadeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1o66C (C:)
slitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpvs
lrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwma
etteflqmrgipvcahigltpqsvfakaqallndakahddagaavvlmecvlaelakkvt
etvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsvqaavrayvaevk
aktfpa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1o66D (D:)
mslitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpv
slrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwm
aetteflqmrgipvcahigltpqsvfafggykvqgrggkaqallndakahddagaavvlm
ecvlaelakkvtetvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsv
qaavrayvaevkaktfpaaehifadeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1o66D (D:)
litvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpvsl
rdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwmae
tteflqmrgipvcahigltpqsvfagkaqallndakahddagaavvlmecvlaelakkvt
etvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsvqaavrayvaevk
aktfpaaeh

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1o66E (E:)
mslitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpv
slrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwm
aetteflqmrgipvcahigltpqsvfafggykvqgrggkaqallndakahddagaavvlm
ecvlaelakkvtetvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsv
qaavrayvaevkaktfpaaehifadeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1o66E (E:)
slitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpvs
lrdmcyhtecvarganamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwmae
tteflqmrgipvcahigaqallndakahddagaavvlmecvlaelakkvtetvscptigi
gagadcdgqvlvmhdmlgifpgktakfvknfmqghdsvqaavrayvaevkaktfpaa