PDB entry 1o4x

View 1o4x on RCSB PDB site
Description: ternary complex of the DNA binding domains of the oct1 and sox2 transcription factors with a 19mer oligonucleotide from the hoxb1 regulatory element
Class: transcription/DNA
Keywords: oct1, pou, pous, pouhd, sox2, hmg-box, transcription factors, DNA, protein-DNA complex, transcription/DNA complex
Deposited on 2003-07-17, released 2004-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-12.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: transcription factor Oct-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14859 (4-End)
      • engineered (64)
    Domains in SCOPe 2.08: d1o4xa1, d1o4xa2
  • Chain 'B':
    Compound: transcription factor sox-2
    Species: Homo sapiens [TaxId:9606]
    Gene: SOX2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1o4xb_
  • Chain 'C':
    Compound: 5'-d(*tp*gp*tp*cp*tp*tp*tp*gp*tp*cp*ap*tp*gp*cp*tp*ap*ap*tp*g)-3'
  • Chain 'D':
    Compound: 5'-d(*cp*ap*tp*tp*ap*gp*cp*ap*tp*gp*ap*cp*ap*ap*ap*gp*ap*cp*a)-3'

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1o4xA (A:)
gshmeepsdleeleqfaktfkqrriklgftqgdvglamgklygndfsqttisrfealnls
fknmaklkpllekwlndaenlssdsslsspsalnspgieglserrkkrtsietnirvale
ksflenqkptseeitmiadqlnmekevirvwfcnrrqkekrinppss

    Sequence, based on observed residues (ATOM records): (download) 
    >1o4xA (A:)
eepsdleeleqfaktfkqrriklgftqgdvglamgklygndfsqttisrfealnlsfknm
aklkpllekwlndaesietnirvaleksflenqkptseeitmiadqlnmekevirvwfcn
rrqkekrin

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1o4xB (B:)
gshmpdrvkrpmnafmvwsrgqrrkmaqenpkmhnseiskrlgaewkllsetekrpfide
akrlralhmkehpdykyrprrktktlmk

    Sequence, based on observed residues (ATOM records): (download) 
    >1o4xB (B:)
drvkrpmnafmvwsrgqrrkmaqenpkmhnseiskrlgaewkllsetekrpfideakrlr
alhmkehpdykyrprrk

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.