PDB entry 1nyu

View 1nyu on RCSB PDB site
Description: Crystal Structure of Activin A Bound to the ECD of ActRIIB
Class: membrane protein/hormone/growth factor
Keywords: activin, type II, tgf beta, actriib, extracellular domain, membrane protein-hormone-growth factor complex
Deposited on 2003-02-13, released 2003-04-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-05-30, with a file datestamp of 2012-05-25.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.268
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: activin receptor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: actrIIb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1nyua_
  • Chain 'B':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1nyub_
  • Chain 'C':
    Compound: activin receptor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: actrIIb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1nyuc_
  • Chain 'D':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1nyud_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1nyuA (A:)
    sgrgeaetreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcw
    lddfncydrqecvateenpqvyfcccegnfcnerfthlpeplvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nyuA (A:)
    treciyynanwelertnqslercegeqdkrlhcyaswrnssgtielvkkgcwlddfncyd
    rqecvateenpqvyfcccegnfcnerfthlpe
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1nyuB (B:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
    tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nyuB (B:)
    lecdgkvicckkqffvsfkdigwndwiiapsgyhanycegecpshilksccvptklrpms
    mlyyddgqniikkdiqnmiveecgcs
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1nyuC (C:)
    sgrgeaetreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcw
    lddfncydrqecvateenpqvyfcccegnfcnerfthlpeplvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nyuC (C:)
    treciyynanwlertnqsglercegeqdkrlhcyaswtielvkkgcwldfncyecvatee
    npqvyfcccegnfcnerfthlpe
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1nyuD (D:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
    tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nyuD (D:)
    cckkffvsiiapsgyhnycegecpccvptklrpmsmlyyddgiikkdiqnmiveecgcs