PDB entry 1nyu
View 1nyu on RCSB PDB site
Description: Crystal Structure of Activin A Bound to the ECD of ActRIIB
Class: membrane protein/hormone/growth factor
Keywords: activin, type II, tgf beta, actriib, extracellular domain, membrane protein-hormone-growth factor complex
Deposited on
2003-02-13, released
2003-04-08
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-10-11, with a file datestamp of
2017-10-06.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.1
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: activin receptor
Species: Rattus norvegicus [TaxId:10116]
Gene: actrIIb
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d1nyua_ - Chain 'B':
Compound: Inhibin beta A chain
Species: Homo sapiens [TaxId:9606]
Gene: INHBA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d1nyub_ - Chain 'C':
Compound: activin receptor
Species: Rattus norvegicus [TaxId:10116]
Gene: actrIIb
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d1nyuc_ - Chain 'D':
Compound: Inhibin beta A chain
Species: Homo sapiens [TaxId:9606]
Gene: INHBA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d1nyud_
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1nyuA (A:)
sgrgeaetreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcw
lddfncydrqecvateenpqvyfcccegnfcnerfthlpeplvpr
Sequence, based on observed residues (ATOM records): (download)
>1nyuA (A:)
treciyynanwelertnqslercegeqdkrlhcyaswrnssgtielvkkgcwlddfncyd
rqecvateenpqvyfcccegnfcnerfthlpe
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1nyuB (B:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
Sequence, based on observed residues (ATOM records): (download)
>1nyuB (B:)
lecdgkvicckkqffvsfkdigwndwiiapsgyhanycegecpshilksccvptklrpms
mlyyddgqniikkdiqnmiveecgcs
- Chain 'C':
Sequence, based on SEQRES records: (download)
>1nyuC (C:)
sgrgeaetreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcw
lddfncydrqecvateenpqvyfcccegnfcnerfthlpeplvpr
Sequence, based on observed residues (ATOM records): (download)
>1nyuC (C:)
treciyynanwlertnqsglercegeqdkrlhcyaswtielvkkgcwldfncyecvatee
npqvyfcccegnfcnerfthlpe
- Chain 'D':
Sequence, based on SEQRES records: (download)
>1nyuD (D:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
Sequence, based on observed residues (ATOM records): (download)
>1nyuD (D:)
cckkffvsiiapsgyhnycegecpccvptklrpmsmlyyddgiikkdiqnmiveecgcs