PDB entry 1nys

View 1nys on RCSB PDB site
Description: Crystal Structure of Activin A Bound to the ECD of ActRIIB P41
Class: membrane protein/hormone/growth factor
Keywords: activin, type II, tgf beta, actriib, extracellular domain, membrane protein/hormone/growth factor complex
Deposited on 2003-02-13, released 2003-04-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: 0.252
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: activin receptor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: actrIIb
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38444
      • see remark 999 (45)
    Domains in SCOPe 2.06: d1nysa_
  • Chain 'B':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1nysb_
  • Chain 'C':
    Compound: activin receptor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: actrIIb
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38444
      • see remark 999 (45)
    Domains in SCOPe 2.06: d1nysc_
  • Chain 'D':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1nysd_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1nysA (A:)
    sgrgeaetreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcw
    lddfncydrqecvateenpqvyfcccegnfcnerfthlpeplvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nysA (A:)
    etreciyynanwelertnqsglercegdkrlhcyaswrnssgtielvkkgcwlddfncyd
    rqecvateenpqvyfcccegnfcnerfthlp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1nysB (B:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
    tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nysB (B:)
    lecdgnicckkqffvsfkdigwndwiiapsgyhanycegecpshilksccvptklrpmsm
    lyyddgqniikkdiqnmiveecgcs
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1nysC (C:)
    sgrgeaetreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcw
    lddfncydrqecvateenpqvyfcccegnfcnerfthlpeplvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nysC (C:)
    etreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcwlddfnc
    ydrqecvateenpqvyfcccegnfcnerfthl
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1nysD (D:)
    glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
    tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nysD (D:)
    icckkqffvsfkdiwndwiiapsgyhanycgecpslksccvptklrpmsmlyyddgqnii
    kkdiqnmiveecgcs