PDB entry 1ny2

View 1ny2 on RCSB PDB site
Description: Human alpha thrombin inhibited by RPPGF and hirugen
Class: hydrolase/hydrolase inhibitor
Keywords: thrombosis, retro binding, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on 2003-02-11, released 2003-03-04
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.202
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

• Chain '1':
  Compound: Thrombin light chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00734 (8-35)
  Domains in SCOPe 2.01: d1ny2.1
• Chain '2':
  Compound: Thrombin heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00734 (0-258)
  Domains in SCOPe 2.01: d1ny2.1
• Chain '3':
  Compound: hirugen
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • Uniprot P28504 (0-9)
• Chain '4':
  Compound: Inhibitor peptide RPPGF
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 1NY2
• Heterogens: HOH

PDB Chain Sequences:

• Chain '1':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ny21 (1:)
  tfgsgeadcglrplfekksledkterellesyidgr
  

  
  
• Chain '2':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1ny22 (2:)
  ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
  vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
  pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
  itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
  thvfrlkkwiqkvidqfge
  

  
  
• Chain '3':
  No sequence available.
  
  
• Chain '4':
  No sequence available.