PDB entry 1nvm

View 1nvm on RCSB PDB site
Description: Crystal structure of a bifunctional aldolase-dehydrogenase : sequestering a reactive and volatile intermediate
Class: lyase/oxidoreductase
Keywords: Sequestered tunnel, substrate channeling, Bifunctional enzyme, LYASE-OXIDOREDUCTASE COMPLEX
Deposited on 2003-02-04, released 2003-06-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxy-2-oxovalerate aldolase
    Species: Pseudomonas sp. [TaxId:79676]
    Gene: DMPG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nvma1, d1nvma2
  • Chain 'B':
    Compound: acetaldehyde dehydrogenase (acylating)
    Species: Pseudomonas sp. [TaxId:79676]
    Gene: DMPF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nvmb1, d1nvmb2
  • Chain 'C':
    Compound: 4-hydroxy-2-oxovalerate aldolase
    Species: Pseudomonas sp. [TaxId:79676]
    Gene: DMPG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nvmc1, d1nvmc2
  • Chain 'D':
    Compound: acetaldehyde dehydrogenase (acylating)
    Species: Pseudomonas sp. [TaxId:79676]
    Gene: DMPF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nvmd1, d1nvmd2
  • Chain 'E':
    Compound: 4-hydroxy-2-oxovalerate aldolase
    Species: Pseudomonas sp. [TaxId:79676]
    Gene: DMPG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nvme1, d1nvme2
  • Chain 'F':
    Compound: acetaldehyde dehydrogenase (acylating)
    Species: Pseudomonas sp. [TaxId:79676]
    Gene: DMPF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nvmf1, d1nvmf2
  • Chain 'G':
    Compound: 4-hydroxy-2-oxovalerate aldolase
    Species: Pseudomonas sp. [TaxId:79676]
    Gene: DMPG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nvmg1, d1nvmg2
  • Chain 'H':
    Compound: acetaldehyde dehydrogenase (acylating)
    Species: Pseudomonas sp. [TaxId:79676]
    Gene: DMPF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nvmh1, d1nvmh2
  • Heterogens: MN, OXL, SO4, MPD, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nvmA (A:)
mtfnpskklyisdvtlrdgshairhqytlddvraiaraldkakvdsievahgdglqgssf
nygfgrhtdleyieavageishaqiatlllpgigsvhdlknayqagarvvrvathctead
vskqhieyarnlgmdtvgflmmshmipaeklaeqgklmesygatciymadsggamsmndi
rdrmrafkavlkpetqvgmhahhnlslgvansivaveegcdrvdaslagmgagagnaple
vfiavaerlgwnhgtdlytlmdaaddivrplqdrpvrvdretlglgyagvyssflrhaei
aaakynlktldilvelghrrmvggqedmivdvaldllaahkenra

    Sequence, based on observed residues (ATOM records): (download) 
    >1nvmA (A:)
tfnpskklyisdvtlrdgshairhqytlddvraiaraldkakvdsievahgdglqgssfn
ygfgrhtdleyieavageishaqiatlllpgigsvhdlknayqagarvvrvathcteadv
skqhieyarnlgmdtvgflmmshmipaeklaeqgklmesygatciymadsggamsmndir
drmrafkavlkpetqvgmhahhnlslgvansivaveegcdrvdaslagmgagagnaplev
fiavaerlgwnhgtdlytlmdaaddivrplqdrpvrvdretlglgyagvyssflrhaeia
aakynlktldilvelghrrmvggqedmivdvaldllaahk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1nvmB (B:)
mnqklkvaiigsgnigtdlmikvlrnakylemgamvgidaasdglaraqrmgvtttyagv
egliklpefadidfvfdatsasahvqneallrqakpgirlidltpaaigpycvpvvnlee
hlgklnvnmvtcggqatipmvaavsrvakvhyaeivasissksagpgtranideftetts
kaieviggaakgkaiiimnpaepplimrdtvyvlsaaadqaavaasvaemvqavqayvpg
yrlkqqvqfdvipesaplnipglgrfsglktsvflevegaahylpayagnldimtsaala
taermaqsmlna

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1nvmC (C:)
mtfnpskklyisdvtlrdgshairhqytlddvraiaraldkakvdsievahgdglqgssf
nygfgrhtdleyieavageishaqiatlllpgigsvhdlknayqagarvvrvathctead
vskqhieyarnlgmdtvgflmmshmipaeklaeqgklmesygatciymadsggamsmndi
rdrmrafkavlkpetqvgmhahhnlslgvansivaveegcdrvdaslagmgagagnaple
vfiavaerlgwnhgtdlytlmdaaddivrplqdrpvrvdretlglgyagvyssflrhaei
aaakynlktldilvelghrrmvggqedmivdvaldllaahkenra

    Sequence, based on observed residues (ATOM records): (download) 
    >1nvmC (C:)
fnpskklyisdvtlrdgshairhqytlddvraiaraldkakvdsievahgdglqgssfny
gfgrhtdleyieavageishaqiatlllpgigsvhdlknayqagarvvrvathcteadvs
kqhieyarnlgmdtvgflmmshmipaeklaeqgklmesygatciymadsggamsmndird
rmrafkavlkpetqvgmhahhnlslgvansivaveegcdrvdaslagmgagagnaplevf
iavaerlgwnhgtdlytlmdaaddivrplqdrpvrvdretlglgyagvyssflrhaeiaa
akynlktldilvelghrrmvggqedmivdvaldllaa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1nvmD (D:)
mnqklkvaiigsgnigtdlmikvlrnakylemgamvgidaasdglaraqrmgvtttyagv
egliklpefadidfvfdatsasahvqneallrqakpgirlidltpaaigpycvpvvnlee
hlgklnvnmvtcggqatipmvaavsrvakvhyaeivasissksagpgtranideftetts
kaieviggaakgkaiiimnpaepplimrdtvyvlsaaadqaavaasvaemvqavqayvpg
yrlkqqvqfdvipesaplnipglgrfsglktsvflevegaahylpayagnldimtsaala
taermaqsmlna

    Sequence, based on observed residues (ATOM records): (download) 
    >1nvmD (D:)
qklkvaiigsgnigtdlmikvlrnakylemgamvgidaasdglaraqrmgvtttyagveg
liklpefadidfvfdatsasahvqneallrqakpgirlidltpaaigpycvpvvnleehl
gklnvnmvtcggqatipmvaavsrvakvhyaeivasissksagpgtranideftettska
ieviggaakgkaiiimnpaepplimrdtvyvlsaaadqaavaasvaemvqavqayvpgyr
lkqqvqfdvipesaplnipglgrfsglktsvflevegaahylpayagnldimtsaalata
ermaqsml

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1nvmE (E:)
mtfnpskklyisdvtlrdgshairhqytlddvraiaraldkakvdsievahgdglqgssf
nygfgrhtdleyieavageishaqiatlllpgigsvhdlknayqagarvvrvathctead
vskqhieyarnlgmdtvgflmmshmipaeklaeqgklmesygatciymadsggamsmndi
rdrmrafkavlkpetqvgmhahhnlslgvansivaveegcdrvdaslagmgagagnaple
vfiavaerlgwnhgtdlytlmdaaddivrplqdrpvrvdretlglgyagvyssflrhaei
aaakynlktldilvelghrrmvggqedmivdvaldllaahkenra

    Sequence, based on observed residues (ATOM records): (download) 
    >1nvmE (E:)
tfnpskklyisdvtlrdgshairhqytlddvraiaraldkakvdsievahgdglqgssfn
ygfgrhtdleyieavageishaqiatlllpgigsvhdlknayqagarvvrvathcteadv
skqhieyarnlgmdtvgflmmshmipaeklaeqgklmesygatciymadsggamsmndir
drmrafkavlkpetqvgmhahhnlslgvansivaveegcdrvdaslagmgagagnaplev
fiavaerlgwnhgtdlytlmdaaddivrplqdrpvrvdretlglgyagvyssflrhaeia
aakynlktldilvelghrrmvggqedmivdvaldllaa

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1nvmF (F:)
mnqklkvaiigsgnigtdlmikvlrnakylemgamvgidaasdglaraqrmgvtttyagv
egliklpefadidfvfdatsasahvqneallrqakpgirlidltpaaigpycvpvvnlee
hlgklnvnmvtcggqatipmvaavsrvakvhyaeivasissksagpgtranideftetts
kaieviggaakgkaiiimnpaepplimrdtvyvlsaaadqaavaasvaemvqavqayvpg
yrlkqqvqfdvipesaplnipglgrfsglktsvflevegaahylpayagnldimtsaala
taermaqsmlna

    Sequence, based on observed residues (ATOM records): (download) 
    >1nvmF (F:)
klkvaiigsgnigtdlmikvlrnakylemgamvgidaasdglaraqrmgvtttyagvegl
iklpefadidfvfdatsasahvqneallrqakpgirlidltpaaigpycvpvvnleehlg
klnvnmvtcggqatipmvaavsrvakvhyaeivasissksagpgtranideftettskai
eviggaakgkaiiimnpaepplimrdtvyvlsaaadqaavaasvaemvqavqayvpgyrl
kqqvqfdvipesaplnipglgrfsglktsvflevegaahylpayagnldimtsaalatae
rmaqsmlna

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1nvmG (G:)
mtfnpskklyisdvtlrdgshairhqytlddvraiaraldkakvdsievahgdglqgssf
nygfgrhtdleyieavageishaqiatlllpgigsvhdlknayqagarvvrvathctead
vskqhieyarnlgmdtvgflmmshmipaeklaeqgklmesygatciymadsggamsmndi
rdrmrafkavlkpetqvgmhahhnlslgvansivaveegcdrvdaslagmgagagnaple
vfiavaerlgwnhgtdlytlmdaaddivrplqdrpvrvdretlglgyagvyssflrhaei
aaakynlktldilvelghrrmvggqedmivdvaldllaahkenra

    Sequence, based on observed residues (ATOM records): (download) 
    >1nvmG (G:)
fnpskklyisdvtlrdgshairhqytlddvraiaraldkakvdsievahgdglqgssfny
gfgrhtdleyieavageishaqiatlllpgigsvhdlknayqagarvvrvathcteadvs
kqhieyarnlgmdtvgflmmshmipaeklaeqgklmesygatciymadsggamsmndird
rmrafkavlkpetqvgmhahhnlslgvansivaveegcdrvdaslagmgagagnaplevf
iavaerlgwnhgtdlytlmdaaddivrplqdrpvrvdretlglgyagvyssflrhaeiaa
akynlktldilvelghrrmvggqedmivdvaldllaahk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1nvmH (H:)
mnqklkvaiigsgnigtdlmikvlrnakylemgamvgidaasdglaraqrmgvtttyagv
egliklpefadidfvfdatsasahvqneallrqakpgirlidltpaaigpycvpvvnlee
hlgklnvnmvtcggqatipmvaavsrvakvhyaeivasissksagpgtranideftetts
kaieviggaakgkaiiimnpaepplimrdtvyvlsaaadqaavaasvaemvqavqayvpg
yrlkqqvqfdvipesaplnipglgrfsglktsvflevegaahylpayagnldimtsaala
taermaqsmlna

    Sequence, based on observed residues (ATOM records): (download) 
    >1nvmH (H:)
klkvaiigsgnigtdlmikvlrnakylemgamvgidaasdglaraqrmgvtttyagvegl
iklpefadidfvfdatsasahvqneallrqakpgirlidltpaaigpycvpvvnleehlg
klnvnmvtcggqatipmvaavsrvakvhyaeivasissksagpgtranideftettskai
eviggaakgkaiiimnpaepplimrdtvyvlsaaadqaavaasvaemvqavqayvpgyrl
kqqvqfdvipesaplnipglgrfsglktsvflevegaahylpayagnldimtsaalatae
rmaqsml