PDB entry 1nrs

View 1nrs on RCSB PDB site
Description: crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes
Class: hydrolase/hydrolase inhibitor
Keywords: SERINE PROTEINASE, RECEPTOR, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 1994-01-18, released 1994-05-31
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.146
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: alpha-thrombin (large subunit)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1nrs.1
  • Chain 'I':
    Compound: hirugen
    Species: Hirudo medicinalis [TaxId:6421]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: alpha-thrombin (small subunit)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1nrs.1
  • Chain 'R':
    Compound: receptor based peptide nrp
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1NRS (0-3)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1nrsH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1nrsH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwgqpsvlqvvnlpiverpvckdstriritdnmf
cagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrl
kkwiqkvidqfg

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1nrsL (L:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records): (download) 
    >1nrsL (L:)
adcglrplfekksledkterellesyi

  • Chain 'R':
    No sequence available.