PDB entry 1nr6

View 1nr6 on RCSB PDB site
Description: microsomal cytochrome p450 2c5/3lvdh complex with diclofenac
Class: oxidoreductase
Keywords: membrane protein, progesterone 21-hydroxylase, benzo(a), pyrene hydroxylase, estradiol 2-hydroxylase, p450, cyp2c5, diclofenac complex, oxidoreductase
Deposited on 2003-01-23, released 2003-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.231
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytochrome p450 2c5
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2C5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00179 (Start-468)
      • engineered (183)
      • engineered (187-188)
      • engineered (190-191)
      • expression tag (469)
    Domains in SCOPe 2.08: d1nr6a1, d1nr6a2
  • Heterogens: SO4, HEM, DIF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nr6A (A:)
makktsskgklppgptpfpiignilqidakdisksltkfsecygpvftvylgmkptvvlh
gyeavkealvdlgeefagrgsvpilekvskglgiafsnaktwkemrrfslmtlrnfgmgk
rsiedriqeearclveelrktnaspcdptfilgcapcnvicsvifhnrfdykdeeflklm
eslhenvellgtpwlqvynnfpalldyfpgihktllknadyiknfimekvkehqklldvn
nprdfidcflikmeqennleftleslviavsdlfgagtettsttlryslllllkhpevaa
rvqeeiervigrhrspcmqdrsrmpytdaviheiqrfidllptnlphavtrdvrfrnyfi
pkgtdiitsltsvlhdekafpnpkvfdpghfldesgnfkksdyfmpfsagkrmcvgegla
rmelflfltsilqnfklqslvepkdlditavvngfvsvppsyqlcfipihhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1nr6A (A:)
gklppgptpfpiignilqidakdisksltkfsecygpvftvylgmkptvvlhgyeavkea
lvdlgeefagrgsvpilekvskglgiafsnaktwkemrrfslmtlrnfgmgkrsiedriq
eearclveelrktnaspcdptfilgcapcnvicsvifhnrfdykdeeflklmeslhenve
llgtpwlqvynnfpalldyfpgihktllknadyiknfimekvkehqklldvnnprdfidc
flikmeqennleftleslviavsdlfgagtettsttlryslllllkhpevaarvqeeier
vigrhrspcmqdrsrmpytdaviheiqrfidllptnlphavtrdvrfrnyfipkgtdiit
sltsvlhdekafpnpkvfdpghfldesgnfkksdyfmpfsagkrmcvgeglarmelflfl
tsilqnfklqslvepkdlditavvngfvsvppsyqlcfipih